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Genetics 210: Personalized Medicine and Genomics. For: MDs, PhDs and curious students Spring term. Tue 2:15 – 4:05 Thur. 2:15-4:05 Genotyping : $15 copay Gene210.stanford.edu: info and FAQs . Today. Course overview (~30’) Informed consent (~30’) How to get genotyped (~10’)

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genetics 210 personalized medicine and genomics

Genetics 210: Personalized Medicine and Genomics

For: MDs, PhDs and curious students

Spring term. Tue 2:15 – 4:05

Thur. 2:15-4:05

Genotyping : $15 copay

Gene210.stanford.edu: info and FAQs

today
Today

Course overview (~30’)

Informed consent (~30’)

How to get genotyped (~10’)

Questions (~15’)

course staff
Course Staff
  • Course Organizers:
    • Stuart Kim (Dev. Bio., Genetics)
    • Aaron Gitler (Genetics)
    • Rosalind Chuang (Neurology)
  • TAs:
    • Andrew Roos (Epidemiology)
    • Thomas Roos (Epidemiology)
genetics 210 personalized medicine and genomics1

Genetics 210: Personalized Medicine and Genomics

Diabetes

Heart Disease

Cancer

Alzheimer’s, Parkinson’s/Huntington’s

slide9

How much Neanderthal are you?

George Church,

Harvard Geneticist

Neanderthal

slide10

Stuart

All time record

slide11

Joint Genotyping Task Force

  • 2008-2010
  • Charles Prober Dean Hank Greely Law School
  • Russ Altman Genetics C. Braddock Med School
  • Pat Brown Biochem. Gil Chu Biochem
  • Mike Grecius Neur. Sean David Med. School
  • Carlos Bustamente Gen. Harry Greenberg Dean
  • Ralph Horwitz Psych Louanne Hudgins Epi
  • Anne James Legal Counsel Jesse Karmazin Med. School
  • Stuart Kim Dev. Bio. Mark KrasnowBiochem
  • Phil Lavori HRP David Magnus Cen. BME
  • Kelly Ormond Genetics Alan Schatzberg Psych.
  • Mike Snyder Genetics Atul Butte BMI
  • KeyanSalari Med. School Mildred Cho Pediatrics
personal genotyping
Personal Genotyping

Voluntary. You can use a public genome file instead of your own.

Confidential – instructors will not know who opted to be genotyped.

Private – Your own DNA information will not be revealed.

Counseling - genetic counseling via 23andMe and medical/psychological counseling via Dr. Alan Schatzberg (Psychology, Stanford).

introductory projects
Introductory Projects

Report on specific genetic locus. Published on SNPedia.com

Class room debate on FDA legislation

Unanticipated opportunities that arise as you explore your genome

advanced projects project final
Advanced Projects = (project + final)

Annotate whole-genome for Stuart Kim or Aaron Gitler (adopted)

Write a grant for Kaiser-Permanente GWAS (n=110,000)

Analyze exome sequence data from ALS patients

Write an algorithm for choosing minimal n number of people to sequence to get all sequence data in a population

gene210
Gene210

Three Manuscripts

Textbook

Patent

Grant

iPhone App

in the news

Chicago Medicine Magazine (story on page 18)

Salon Web Magazine (9/2013)

Stanford Medicine - DNA testing improves learning (8/13)

San Jose Mercury News (5/2013)

Time (2/2013)

Nature

USA Today

San Francisco Chronicle Recap

San Francisco Chronicle

Genome Technology

Stanford Press Release

Nature Blogs

LA Times Blog

Genome Web

Center for Genetics and Society

Scientific American

how to get genotyping kits

How to get genotyping kits

Attend this information session.

Make check $15 to Stanford.

Bring check to Kathy Fisher in Beckman B300.

Fill out informed consent form

Bring samples back to Kathy B300

We will ship the group of samples back to company Tuesday 4pm Feb. 4

Results in 6-8 weeks.

Class starts Tuesday April 1, 2012.

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