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Duke Translational Medicine Institute

Duke Translational Medicine Institute. Duke University. The Cycle of Quality: Generating Evidence to Inform Policy. 3. 2. 4. 1. Data Standards. NIH Roadmap. Network Information. FDA Critical Path. Early Translational Steps. 5. Empirical Ethics. Discovery Science. 6.

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Duke Translational Medicine Institute

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  1. Duke Translational Medicine Institute Duke University

  2. The Cycle of Quality: Generating Evidence to Inform Policy 3 2 4 1 DataStandards NIH Roadmap NetworkInformation FDACritical Path Early TranslationalSteps 5 EmpiricalEthics Discovery Science 6 Prioritiesand Processes Measurement andEducation ClinicalTrials Outcomes 12 7 Transparencyto Consumers Inclusiveness 11 8 ClinicalPracticeGuidelines Pay forPerformance PerformanceMeasures Use forFeedbackon Priorities 9 10 Conflict-of-interestManagement Evaluation of Speedand Fluency Source: Califf RM et al, Health Affairs, 2007

  3. Discovery to Care Continuum Source: Dzau et al, Lancet 2009

  4. Current Fragmented Approach Source: Dzau et al, Lancet 2009

  5. Duke Medicine Model for Translation Source: Dzau et al, Lancet 2009

  6. Duke Medicine Viewpoint:Vertical Integration of Care Delivery Source: Dzau et al, Lancet 2009

  7. DTMI Mission • To catalyze translation across the continuum of scientific discovery, clinical research, care delivery, and global health

  8. What is the DTMI? • Duke’s academic home for the clinical and translational research community • A service-oriented platform that provides resources and training for clinical and translational research • An integrated support structure that facilitates collaborative researchacross departments, centers, institutes, and schools • A catalyst for innovation in the translation of research from discovery to practice and back

  9. DTRI DCRU DCRI DTNI DCCR Duke Translational Research Institute Duke Clinical Research Unit Duke Clinical Research Institute Duke Translational Nursing Institute Duke Center for Community Research Biomedical Informatics Biostatistics Core Laboratories Education and Training Ethics Child Health Project Leadership Regulatory Affairs Site-based Research DTMI Duke Translational Medicine Institute Duke Global Health Institute Discovery Science First-in-human Application at the point of care Preclinical research Proof of Concept Phase II–IV Application in the community

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