oxidative decarboxylation
Download
Skip this Video
Download Presentation
Oxidative Decarboxylation

Loading in 2 Seconds...

play fullscreen
1 / 21

Oxidative Decarboxylation - PowerPoint PPT Presentation


  • 302 Views
  • Uploaded on

Oxidative Decarboxylation. Oxidative Decarboxylation. Oxidative Decarboxylation. Pyruvate is converted into acetyl- CoA in order to be brought into the mitochondria. Oxidative Decarboxylation. rxn type: decarboxylation redox synthesis enzyme: decarboxylase dehydrogenase

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about ' Oxidative Decarboxylation' - kenneth-rice


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
oxidative decarboxylation2
Oxidative Decarboxylation

Pyruvate is converted into acetyl-CoAin order to be brought into the mitochondria.

oxidative decarboxylation3
Oxidative Decarboxylation

rxn type: decarboxylation

redox

synthesis

enzyme: decarboxylase

dehydrogenase

synthase

energy: released

coenzyme a
Coenzyme A

Coenzyme A is a large organic molecule.

The active functional group is a thiol.

It is also written as

CoA-SH.

oxidative decarboxylation summary
Oxidative Decarboxylation Summary
  • 2 pyruvate 2 acetyl-CoA
  • 2 CO2 released
  • 2 NADH produced
krebs cycle overview
Krebs Cycle Overview

Krebs cycle is a cyclical process to:

  • produce additional CO2 molecules
  • generate more high energy molecules (NADH, FADH2 and ATP)

Also known as the citric acid cycle and the tricarboxylic acid cycle (TCA).

krebs cycle step by step
Krebs Cycle: Step by Step

Step 1:

  • join 2 carbon molecule with a 4 carbon molecule
  • rxn type: synthesis
  • enzyme: synthase
  • energy: absorbed
krebs cycle step by step1
Krebs Cycle: Step by Step

Step 2:

  • rearrangement of atoms with the help of H2O
  • rxn type: isomerization
  • enzyme: isomerase
  • energy: equivalent
krebs cycle step by step2
Krebs Cycle: Step by Step

Step 3:

  • synthesis of CO2 and NADH
  • rxn type: decarboxylation

redox

  • enzyme: decarboxylase

dehydrogenase

  • energy: released
krebs cycle step by step3
Krebs Cycle: Step by Step

Step 4:

  • CO2 release and energy molecule formation
  • rxn type: decarboxylation

redox

synthesis

  • enzyme: decarboxylase

dehydrogenase

synthase

  • energy: released
krebs cycle step by step4
Krebs Cycle: Step by Step

Step 5:

  • ADP phosphorylation to ATP
  • rxn type: substrate-level phosphorylation

cleavage

  • enzyme: kinase

lyase

  • energy: released
krebs cycle step by step5
Krebs Cycle: Step by Step

Step 6:

  • FADH2 (energy molecule) formation
  • rxn type: redox
  • enzyme: dehydrogenase
  • energy: released
fad fadh 2
FAD / FADH2
  • FAD – flavin adenine dinucleotide (oxidized form)
  • FADH2 – flavin adenine dinucleotide (reduced form)
krebs cycle step by step6
Krebs Cycle: Step by Step

Step 7:

  • rearranging the molecule for the next reaction
  • rxn type: hydration
  • enzyme: hydrase
  • energy: absorbed
krebs cycle step by step7
Krebs Cycle: Step by Step

Step 8:

  • energy molecule formation & recreating molecules for Krebs cycle
  • rxn type: redox
  • enzyme: dehydrogenase
  • energy: released
krebs cycle summary
Krebs Cycle Summary
  • two cycles of Krebs for EACH glucose molecule
  • acetyl-CoA oxaloacetate (per cycle)
  • 2 CO2 released (per cycle)
  • 3 NADH produced (per cycle)
  • 1 FADH2 produced (per cycle)
  • 1 ATP produced (per cycle)
krebs cycle big picture perspective
Krebs Cycle: Big Picture Perspective

Many of the components of Krebs cycle are used in many other types of metabolic processes.

ad