Primary immunodeficiencies in adults lithuanian experience
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Primary immunodeficiencies in adults (Lithuanian experience). Audra Blažienė Vilnius university Lithuania 2006. Primary immunodeficiencies. Suspicion for PID. Recurrent or chronic infections such as middle ear infection, sinus infections or pneumonia.

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Primary immunodeficiencies in adults (Lithuanian experience)

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Primary immunodeficiencies in adults lithuanian experience

Primary immunodeficiencies in adults(Lithuanian experience)

Audra Blažienė

Vilnius university

Lithuania

2006


Primary immunodeficiencies

Primary immunodeficiencies


Suspicion for pid

Suspicion for PID

  • Recurrent or chronic infections such as middle ear infection, sinus infections or pneumonia.

  • A history of prolonged illness for which treatments with antibiotics are ineffective.

  • A rapid return of an illness once it is been treated.


Dilemmas in diagnosis and management

Dilemmas in diagnosis and management

  • How deep evaluation must be for individual patient?

  • What tests are useful?

  • What complications may occur in these diseases?

  • What treatments can be used in these cases?


Pid in adults

PID in adults

  • Selective IgA deficiency

  • Common variable immunodeficiency (CVID)

  • IgG subclass deficiency

  • X-linked agammaglobulinemia

  • Phagocytic cells disorders

  • Disorders of the complement system


Primary immunodeficiencies in adults lithuanian experience

Vilnius


Pid diagnosed in vuh

PID diagnosed in VUH

  • CVID – 5 cases

  • Agammaglobulinemia (B cells absent) – 1 case

  • C1 esterase deficiency – 2 cases


Pid in vuh

PID in VUH

  • First case of CVID had been confirmed in 1998 and antibody replacement therapy with intravenous immunoglobulin ( Endobulin) was started.


Future

FUTURE

  • PID register

  • Improvement in diagnostic methods

  • More active search for new cases of PID


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