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GEMSS : G rid- E nabled M edical S imulation S ervices

GEMSS : G rid- E nabled M edical S imulation S ervices. Healthgrid Cluster Meeting Project Overview: Profile from CORDIS Consortium Project Goals / Objectives GEMSS System Design Medical Applications Clustering IST-2001-37153. GEMSS Project Profile (Cordis).

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GEMSS : G rid- E nabled M edical S imulation S ervices

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  1. GEMSS: Grid-Enabled Medical Simulation Services Healthgrid Cluster Meeting Project Overview: Profile from CORDIS Consortium Project Goals / Objectives GEMSS System Design Medical Applications Clustering IST-2001-37153

  2. GEMSS Project Profile (Cordis) Project Acronym: GEMSS Title: GRID-enabled Medical Simul. Services Subject Index :Policies; Legislation, Regulations;Information Processing, Information Systems; Electronics, Microelectronics Start Date:2002-09-01End Date:2005-02-28Duration:30 Ms Project Status: Accepted Project Cost: 3.59 million € Funding: 2.63 million € Programme Type: 5th FWP (Fifth Framework Programme) Programme Acronym : IST Subprogramme Area: Cross Programme Actions (CPA) – CPA9: Grid test beds, deployment and technologies Project Reference: IST-2001-37153 Contract Type: CSC (Cost-sharing contracts)

  3. No Partner Role Country Specific Expertise 1 NEC C C&C R.L. UK (Germany) 2 MPI P Germany 3 ISS P Austria 4 USFD P STH S UK 5 AEA P UK 6 IT- P Innovation UK 7 CRID P Belgium Grid Software /solutions Bio-numeric modelling Simulation/Imaging SW Medical Expertise Legal Aspects 8 ASD A Germany 9 IDAC A Ireland 10 IBMTP A Austria GEMSS Consortium Legend: C – Co-ordinator P – Principal Contractor S – Subcontractor A – Associate Contractor

  4. The main goals of GEMSS are : • Install an extendible, interoperable and collaborative testbed for GRID-enabled medical application services, • Demonstrate the medical significance of the GEMSS models, • Demonstrate the functionality of the GRID-infrastructure, • Open a business model for future commercial exploitation.

  5. Simulation portal A general overview / possible scenario Medical simulation service Portal + networked compute resources User-site (SW installed) Simulation Service System GRID SW (interface) GRID SW Pre- & Post- processing Applications SW GRID SW (service use) Internet or Intranet Could also be moved to the services portal

  6. GEMSS Project Objectives GEMSS will demonstrate that the Grid can be used to provide medical practitioners and researchers with access to advanced simulation and image processing services for improved pre-operative planning and near real-time surgical support. The GEMSS will build on top of existing Grid technologies, maintaining compliance with standards thereby ensuring future extensibility and interoperability, to provide support for authorisation, workflow, security, error detection and recovery. Test-bed to evaluate & validate the GEMSS environment, including its integration into the end-users working environments. GEMSS aims to anticipate privacy, security and other legal concerns by examining and incorporating into its Grid services the latest laws and EU regulations related to providing medical services over the Internet.

  7. GEMSS System Design Generic GRID-services: build on existing GRID and WEB technologies like OGSA, Web services, Jini and Corba, service interaction models, protocols & interfaces, QoS (time critical services), security models compliant with European legal issues, fail-over and recovery from errors, workflow and service orchestration techniques for time-critical processes, medical GRID portals, PSEs, application servers. Medical service applications: Numerical modelling, based on existing software packages such as CFX and EASA, High Performance Computing (HPC) simulation, FE analysis, Advanced image processing. Collaborative tools: tele-support, tele-consulting.

  8. Grid Architecture Application Layer Collective Layer Resource Layer Fabric Layer Applications, Portals, Environments Higher Services, APIs, Protocols APIs, Protocols, SDKs Computers, Networks, Devices

  9. Grid Architecture Application Layer Collective Layer Resource Layer Fabric Layer Applications, Portals, Environments Higher Services, APIs, Protocols Globus toolkit APIs, Protocols, SDKs Computers, Networks, Devices

  10. Condor Grid Architecture Application Layer Collective Layer Resource Layer Fabric Layer Applications, Portals, Environments Higher Services, APIs, Protocols APIs, Protocols, SDKs Computers, Networks, Devices

  11. Legion Grid Architecture Application Layer Collective Layer Resource Layer Fabric Layer Applications, Portals, Environments Higher Services, APIs, Protocols APIs, Protocols, SDKs Computers, Networks, Devices

  12. UNICORE Grid Architecture Application Layer Collective Layer Resource Layer Fabric Layer Applications, Portals, Environments Higher Services, APIs, Protocols APIs, Protocols, SDKs Computers, Networks, Devices

  13. UNICORE Legion Condor Grid Architecture Application Layer Collective Layer Resource Layer Fabric Layer Applications, Portals, Environments Higher Services, APIs, Protocols Globus toolkit APIs, Protocols, SDKs Computers, Networks, Devices Which one to use?

  14. GEMSS: Medical Applications Maxillo-facial Surgery Simulation During maxillo-facial surgery a steel device is tightly fixed to the head by special screws. These screws deform the skull which becomes clearly visible as a result of a parallel finite element analysis. The goal is to provide a virtual planning space for the optimisation the fixation and distraction procedures. Partners: NEC MPI Test-bed Applications (1) Maxillo-facial surgery simulation. (2) Neuro-surgery support. (3) Radio-surgery simulation. (4) Inhaled drug-delivery simulation. (5) Cardio-vascular system simulation. (6) Advanced image reconstruction. Phase I: Halo positioning Phase II: Distraction Procedure

  15. GEMSS: Medical Applications Neuro Surgery Support Prediction of the brain shift during neurosurgery is important to provide co-ordinates for the surgical navigation. In GEMSS a robust and precise approach based on non-linear image registration will be implemented in a Grid environment. Partner(s): MPI Test-bed Applications (1) Maxillo-facial surgery simulation. (2) Neuro-surgery support. (3) Radio-surgery simulation. (4) Inhaled drug-delivery simulation. (5) Cardio-vascular system simulation. (6) Advanced image reconstruction.

  16. GEMSS: Medical Applications Radio-surgery simulation Revised treatment plan simulated - different beam weighting and orientation RAPT simulation now shows better coverage - differs from conventional treatment analysis New treatment more likely to be successful. Partner(s): IT-Innovation, USFD Test-bed Applications (1) Maxillo-facial surgery simulation. (2) Neuro-surgery support. (3) Radio-surgery simulation. (4) Inhaled drug-delivery simulation. (5) Cardio-vascular system simulation. (6) Advanced image reconstruction.

  17. GEMSS: Medical Applications Inhaled Drug-Delivery Simulation Take-up of the Cophit project – A combination of computational fluid dynamics and 1-dimensional models to optimise delivery of inhaled drugs to the lung. Partner(s): USFD, AEA, ASD Test-bed Applications (1) Maxillo-facial surgery simulation. (2) Neuro-surgery support. (3) Radio-surgery simulation. (4) Inhaled drug-delivery simulation. (5) Cardio-vascular system simulation. (6) Advanced image reconstruction.

  18. GEMSS: Medical Applications Cardio-vascular System Simulation A compartmental approach and coupled structural mechanics and fluid dynamics will be applied to simulate the entire cardio-vascular system. Partner(s): USFD, AEA, ASD, IDAC Test-bed Applications (1) Maxillo-facial surgery simulation. (2) Neuro-surgery support. (3) Radio-surgery simulation. (4) Inhaled drug-delivery simulation. (5) Cardio-vascular system simulation. (6) Advanced image reconstruction. Heart-valve example kindly provided by the BLOODSIM project.

  19. Hospital A Internet ... Hospital Z Reconstruction Service GRID Agent ... Reconstruction Service GEMSS: Medical Applications Advanced Image Reconstruction Entropy-based parallel Projection Image Reconstruction for SPECT. The medical image reconstruction system is based on a service oriented architecture to provide clients with advanced fully 3D image reconstruction services running transparently on remote parallel computers. Partner(s): ISS, IBMTP Test-bed Applications (1) Maxillo-facial surgery simulation. (2) Neuro-surgery support. (3) Radio-surgery simulation. (4) Inhaled drug-delivery simulation. (5) Cardio-vascular system simulation. (6) Advanced image reconstruction.

  20. Healthgrid Cluster Activities • GEMSS contributions: • Participation in the GGF. • Participation in GridStart. • Establish contact with related projects to identify common interests and synergies. • Consolidation of technical developments. • Identification of possible tool sharing. • Interoperability and standardisation efforts. • Common dissemination in health-related events.

  21. Suggestions for Clustering • CROSSGRID As the first application, a Grid-based prototype system for pre-treatment planning in vascular interventional and surgical procedures will be developed through real-time interactive simulation of vascular structure and flow. The system consists of a distributed real-time simulation environment, in which a user interacts in Virtual Reality (VR). A 3D model of the arteries, derived using medical imaging techniques, will serve as input to a real-time simulation environment for blood flow calculations. The user will be allowed to change the structure of the arteries, thus mimicking a surgical procedure and the effects of this adaptation will be analysed in real time while the results are presented to the user in a virtual environment.

  22. Suggestions for Clustering • CROSSGRID + GEMSS common interests: Simulation/visualisation, Medical LBA (Lattice Boltzmann for scan data)

  23. Suggestions for Clustering • EUROGRID (Bio/Meteo/CAE-GRID) • The objectives of the EUROGRID project are: • To establish a European GRID network of leading High Performance Computing centres from different European countries. • To operate and support the EUROGRID software infrastructure. The EUROGRID software will use the existing Internet network and will offer seamless and secure access for the EUROGRID users. • To develop important GRID software components and to integrate them into EUROGRID (fast file transfer, resource broker, interface for coupled applications and interactive access).  • To demonstrate distributed simulation codes from different application areas (Biomolecular simulations, Weather prediction, Coupled CAE simulations, Structural analysis, Real-time data processing). • To contribute to the international GRID development and to liase with the leading international GRID projects. • To productise the EUROGRID software components. After project end the EUROGRID software will be available as supported product.

  24. Suggestions for Clustering • EUROGRID+ GEMSS common interests: UNICORE Bio-GRID HPC GRID

  25. GEMSS: Contact & Info Contact: fingberg@ccrl-nece.de Dr. Jochen Fingberg C&C Research Laboratories NEC Europe Ltd. Tel. +49 2241 92520 Project site: http://www.gemss.de Cordis: http://dbs.cordis.lu

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