CHRONIC HEPATITIS C IMPAIRS PSYCHOMOTOR FUNCTIONS OF INFECTED SUBJECTS. Ilona Savlan, Valentina Liakina, Jonas Valantinas. Clinic of Gastroenterology, Nephrourology and Surgery Vilnius University, Vilnius, Lithuania. Introduction.
Ilona Savlan, Valentina Liakina, Jonas Valantinas
Clinic of Gastroenterology, Nephrourology and Surgery
Vilnius University, Vilnius, Lithuania
Hepatic encephalopathy is a neuropsychiatric complication of liver cirrhosis the symptoms of which may vary from imperceptible to severe, invaliding, and even lethal.
According to the published data hepatitis C infection causes abnormalities of cognitive and motor functions which persist even after successful elimination of the virus.
Aim: To evaluate differences in psychometric tests results of chronic hepatitis C (CHC) patients and healthy control.
42 (22/52.4% men and 20/47.6% women; mean age 43.1±15.3) CHC patients and 12 healthy persons (control group: 5/41.7% men, 7/58.3% women; mean age 43.6±09.2) were tested.
All participants were invited to perform these tests:
the number connection tests A and B (NCT-A, NCT-B) and the digit-symbol (DST) test.
Statistical analysis was performed with SPSS 17.0 software. Differences in the tests results between control and CHC patients were evaluated with chi-square test.
We did not find statistically significant correlation between psychometric tests time-span and education, tests results did not depend on participant's gender either. In the both tested groups alder participants performed tests slower than younger one, nevertheless, CHC patients tests time-span was longer than in controls, but this finding was not statistically proved maybe because of insufficient amount of tested persons.
CHC patients have performed psychometric tests more slowly than healthy control of the same age and gender distribution. Those results can be explained by impairment of cognitive and motor functions in CHC patients.