CHAPTER 5 DNA REPLICATION, REPAIR AND RECOMBINATION. THE MAINTENANCE OF DNA SEQUENCES DNA REPLICATION MECHANISMS THE INITIATION AND COMPLETION OF DNA REPLICATION IN CHROMOSOMES DNA REPAIR GENERAL RECOMBINATION SITE-SPECIFIC RECOMBINATION. THE MAINTENANCE OF DNA SEQUENCES.
Cis acting DNA sites - end sequences (red)
Trans-acting Protein factors - transposase (blue)
Transposons are compound elements
coordinated transcription and site specific recombination
Transposase is encoded by A and B genes
C represses expression of (almost) all other genes
Gin is a site specific recombinase
The Mu C protein (AKA Repressor, Rep) is analogous to the lambda repressor
TS mutants repress at the permissive temperature but fail to function at higher temperatures.