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第 32 章 疱疹病毒 PowerPoint PPT Presentation


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第 32 章 疱疹病毒. 疱疹病毒( Herpesviruses )是一类中等大小、结构相似、有包膜的双链 DNA 病毒。现已发现 114 种,分为 α 、 β 、 γ 三个亚科。 目前发现的人类疱疹病毒有 8 种。. 人类疱疹病毒名称及亚科. 包膜糖蛋白. 壳粒. 壳粒. DNA. 皮层. 人类疱疹病毒的共同特征:. 形态:. 复制: 在 细胞核内 复制和装配,通过核膜出芽,由胞吐或细胞溶解方式释放病毒。能使细胞融合形成多核巨细胞。. 感染类型: ① 显性感染 ② 潜伏感染 ③ 整合感染: 致癌 疫苗制备 ④ 先天性感染. 第一节 单纯疱疹病毒.

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第 32 章 疱疹病毒

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  • HerpesvirusesDNA114

  • 8


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DNA


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32


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  • HSV


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  • HSV-1HSV-2DNA50

  • HSV11gBgC gD gEgG gH gI gJ gK gL gM


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HSV


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  • CPE


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  • HSV-1HSV-2

  • HSV80~90


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HSV

1 HSV-16M2Y

HSV-2


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2

HSV

HSV-1


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3

4 HSV-2

  • HSV


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  • ACV


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-

  • -VZVvaricellazoster

  • HSV


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  • 3~9


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39

20%30%


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32


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  • VZV

  • VZVIg


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EB

  • EB1964EpsteinBarr(Burkitt lymphoma) EB(Epstein-Barr virus,EBV)


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  • EBV

  • EBVEBV


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  • EBV

    EBV(EBNA) (LMP)

    EBV (EA)EBV(VCA)EBV(MA)


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  • EBV35EBV90


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  • EBV

  • BEBVCD21CR2


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  • EBV


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1

2


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  • HCMV)


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  • 712dCPE


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  • CMV2 60%90%CMV


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  • 1

    2

    3

    4


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1CIDHCMV


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  • IgMIgAHCMVIgM


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  • HCMV


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