Module 6: Manufacturing Throughput. Module 6 Purpose and Objectives. Module Purpose: Process optimization requires understanding the process. The student will examine the variables involved with sublimation and then review “whole manufacturing cycles”. Module Objectives:
Constraints: Filling begins on the day shift.
Ergo: The complete lyo manufacturing cycle has to be an integral number of days.
Slack Time: Some built in slack time may be needed in order to keep to a schedule.
Making the Lyo Cycle shorter can’t really help.
A longer “secondary dry” with a new temperature permits the design of a “convenient” cycle.
Recommend a manufacturing cycle for a vaccine filling operation that has an optimized drying cycle of 12 hours. Assume