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Hibernation, Aging and Longevity. Natalia S. Gavrilova Leonid A. Gavrilov Center on Aging, NORC/University of Chicago, 1155 East 60th Street, Chicago, IL 60637. Study of Turkish hamsters, Science, 1981. Hibernation and longevity. a) Longevity of all hamsters in the study.

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Hibernation aging and longevity

Hibernation, Aging and Longevity

Natalia S. Gavrilova

Leonid A. Gavrilov

Center on Aging, NORC/University of Chicago,

1155 East 60th Street, Chicago, IL 60637



Hibernation and longevity
Hibernation and longevity

a) Longevity of all hamsters in the study.

b) Longevity of the poor, moderate and good hibernators in the study



Distribution of deaths in a control and b experimental hamsters
Distribution of deaths in (a) control and (b) experimental hamsters

  • Number of deaths against age at death at intervals of 60 days for

    a) control hamsters (mean = 812 days, median = 843 days)

    b) experimental hamsters (mean = 914 days, median = 884 days)



Hibernation and longevity in bat species
Hibernation and Longevity in Bat Species hamsters

(a) Average longevity for bat species that do and do not hibernate.

  • Numbers indicate sample size in each category.

    (b) Average change in longevity between phylogenically independent comparisons in which hibernation was acquired.



Hibernation is not continuous

Hibernation is not continuous! and bivariate analysis of contrasts

There are cycles of hibernation and short awakening

(every week in ground squirrels)


You don t need to hibernate in order to delay aging
You don't need to hibernate and bivariate analysis of contrastsin order to delay aging:

Hibernation signals (darkness) may be sufficient!


Study of siberian hamster
Study of Siberian Hamster and bivariate analysis of contrasts


Day length and reproductive success in females of siberian hamsters
Day length and reproductive success in females of Siberian hamsters

A) Reproductive success of long-day (LD), short-day (SD) and short-day pinealectomized (SD-PX) females expressed as the percentage of females mated at 9 mo of age that delivered live litters.

B) Mean + SEM live litter size at birth and weaning.


Short day exposure and delaying reproductive senescence in females of siberian hamster
Short-day exposure and delaying reproductive senescence in females of Siberian hamster

  • Mean + SEM number of primordial follicles per ovary in SD and LD females at 13 and 26 wk of age. Asterisk (*) denotes significant effect of photoperiodic treatment at both ages


Growth curves for hamsters subjected to ld and sd exposure
Growth curves for hamsters subjected to LD and SD exposure females of Siberian hamster

  • Mean + SEM body mass (grams) of LD, SD, and SD-PX females from weaning at Postnatal Day 18 to 40 wk of age.


Conclusion
Conclusion: females of Siberian hamster

Лампочка Ильича ускоряет старение!


Study of black bears
Study of Black Bears females of Siberian hamster


Black bear active and hibernating
Black bear: females of Siberian hamsteractive and hibernating


Hibernating bears are hot
Hibernating Bears are Hot! females of Siberian hamster

  • Body temperature: 30 - 34 C Reference: Carey HV, Andrews MT, Martin SL.  Mammalian hibernation: cellular and molecular responses to depressed metabolism and low temperature. Physiol Rev. 2003 Oct;83(4):1153-81. Review. PMID: 14506303



What About Humans? females of Siberian hamster


For more information and updates visit our website
For More Information and Updates Visit Our Website: females of Siberian hamster

http://longevity-science.org

You are Welcome to Post Your Comments at our Blog:

http://longevity-science.blogspot.com/


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