Efficacy of Single Dose IV
This presentation is the property of its rightful owner.
Sponsored Links
1 / 21

Efficacy of Single Dose IV Hydrocortisone in Post Traumatic Stress Disorder (PTSD) Prevention PowerPoint PPT Presentation


  • 91 Views
  • Uploaded on
  • Presentation posted in: General

Efficacy of Single Dose IV Hydrocortisone in Post Traumatic Stress Disorder (PTSD) Prevention. Dr. Yahalom Hila Prof. Zohar Joseph Dr. Cwikel-Hamzany Shlomit Dr. Bar- Ziv Danit Sheba Medical Center. כ- ½ ע ד 2/3 מהאוכלוסייה יחשפו לאירוע טראומטי בשלב כלשהו בחייהם

Download Presentation

Efficacy of Single Dose IV Hydrocortisone in Post Traumatic Stress Disorder (PTSD) Prevention

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

Efficacy of Single Dose IVHydrocortisone in Post Traumatic StressDisorder (PTSD) Prevention

Dr. Yahalom Hila

Prof. Zohar Joseph

Dr. Cwikel-HamzanyShlomit

Dr. Bar-ZivDanit

Sheba Medical Center


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

  • - 2/3

  • - National Comorbidity Survey PTSD - 7%

    Kessler et al ; Arch Gen Psychiatry, 2005


Outside the range of human experience

"Outside the range of human experience"?


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

PTSD- ?

  • .

  • 4 PTSD :

  • BETA BLOCKERS (PROPRANOLOL)

  • BENZODIAZEPINES

  • MORPHINE

  • SSRIs


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

  • Beta Blockers - PROPRANOLOL

  • .

  • Pitman et al; Biol Psych. 2002.

  • Vaiva et al; Biol Psych. 2003.

  • Stein et al; Journal of Traumatic Stress. 2007.


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

  • ' (2-18). (9 3 - PTSD 6 )

    Gelpin E, Bonne O, Peri T, Brandes D, Shalev AY; J Clin Psychiatry. 1996.


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

  • PTSD

  • Holbrook TL, Galarneau MR, Dye JL, Quinn K, Dougherty AL.N Engl J Med. 2010


Ssri s

SSRIs

  • ' PTSD - ESCITALOPRAM


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

PTSD?

  • "" (plasticity) HPA PTSD

  • . "" - PTSD


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

  • ' PTSD

    Schelling G et al; Ann N Y Acad Sci. 2006

  • ' PTSD

    Cohen H, Matar MA, Buskila D, Kaplan Z, Zohar J; Biol Psychiatry. 2008


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

  • - golden hours

    ( TPA - STROKE

    - MI)?

  • ?

  • PTSD?


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

" " - PTSD?

Window of Opportunities?

Time from trauma

ASD

ACUTE PTSD

CHRONIC PTSD

6 hours

4 weeks

3 month


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

PTSD?

  • 24 "

    ( =20, =4).

  • IV

    (100-140 ") (n=14) (n=10)

  • 6

  • ,

  • , , CAPS


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

24

19 (=9, = 10)

13 (=5, = 8)

14 3 (=5, = 7)

  • ' , "


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

  • , 1 8 ASD (12.5%) 7 9 (77.7%)

  • , 1 6 - PTSD (16%), 3 5 (60%)

  • 3 , 1 7 - PTSD(14.3%), 3 5 (60%)


Efficacy of single dose iv hydrocortisone in post traumatic stress disorder ptsd prevention

CLINCIAN ADMINISTERD PTSD QUESTIONNAIRE (CAPS) ( ) - PTSD

CAPS

(average)


Golden hours in psychiatry

Golden hours in psychiatry?

  • PTSD

  • PILOT

  • . PTSD


  • Login