Course Structure

1. PhD Programme2013/2014Palacký University FacultyofMedicine and Dentistry, OlomoucExploitingLiteratureDatabasesEnglishVersionCourseteacher & developer:J. Potomková, Ph.D.jarmila.potomkova@upol.czPalackyUniversityMedicalLibrary & InstituteofMedicalBiophysicsMedicaladvisor: V. Mihál, Prof., MD, PhD.HeadofPalackýUniversityPaediatricDepartmentlE-learningmaterials in Czechhttp://biomedicina.upol.cz/moodle

2. CourseStructure • Introduction • Contacts • Usefulllinks • Electronicinformationresourcesat Palacký University Olomouc • Remoteaccess • Clinical case, researchquestion, PICO • Informationretrievalusingmultipleresources • Theory • Interactive online training • Discussion, exercise • Conclusion.

3. Contacts Jarmila Potomková, PhD. Palacký University MedicalLibrary, Director Institute ofMedicalBiophysics, Senior Lecturer jarmila.potomkova@upol.cz Vladimír Mihál, Prof., MD., PhD. Palacký University & TeachingHospital Department ofPaediatrics, Head mihalv@fnol.cz Palacký University MedicalLibrary, Website http://www.lf.upol.cz – Knihovna –Vzdělávání(Training) --- DSP „QAKOM“ – e-learningportalfor PhD programmes http://biomedicina.upol.cz/moodle -- Kurzy/B001/Czech version

4. UsefulLinks • Palacký University Library, Olomouc http://katalog.upol.cz Online public accesscatalog • ResearchLibrary, Olomouc http://www.vkol.cz . • NationalMedicalLibrary, Prague http://www.nlk.cz – Fee-basedregistrationforremotedatabase access http://www.medvik.cz/bmc – BibliographiaMedicaČechoslovaca • NationalLibraryofMedicine (USA) http://www.locatorplus.gov – Bookcatalog http://www.pubmed.gov – Database MEDLINE • WorldCat http://www.worldcat.org WorldCat is the world's largest network of library content and services. WorldCat libraries are dedicated to providing access to their resources on the Web, where most people start their search for information. • SearchEngines http://www.google.com - General search http://scholar.google.com - Scientificarticlesonly http://books.google.com - Bookcontentforreadingonly http://www.yahoo.com http://www.bing.com

5. ElectronicInformationResourcesat Palacký University • ABC, faculties, fields http://ezdroje.upol.cz • Medicaldatabases http://www.lf.upol.cz/ Knihovna LF Databáze • Free (PubMed http://www.pubmed.gov) • IP-recognition • Palacký University network (eg. Dynamedhttp://search.epnet.com) • TeachingHospital Olomouc (eg. UpToDatehttp://www.uptodate.com/online) • Remoteaccess • VPN (VirtualPrivate Network) • Shibboleth / eduID • Terminal Server For more detailsfeel free to contact: Mr. Tomáš Kopečný, network administrator (tomas.kopecny@upol.cz)

6. Clinicalcase (scenario) ResearchQuestionFormulation, PICO Format

7. Clinical Case (author: V. Mihál) A boy, 2 yearsold • Acute otitis media; • Fever, earache; • Visit to a paeditrician´soffice; • Pharmacologicalanamnesis • No ATBs in the past 6 months; • No pneumococcalvaccination; • Motherwants to knowwhetherantibiotics(eg. amoxicillin) shouldbeprecscribedimmediately………

8. Formulationof a PICOQuestionBeforeSearch Patient(s)/problem/population • Otitis media in infants (birth - 2 years) Intervention/exposure • Immediateantibiotictherapy (eg. amoxicilin) Comparison • Painkiller– placebo – watch-and-see Outcome • Effectoftheselectedintervention

9. Searchterms, keywords„Minimum InformationPrinciple“ P • (Acute) otitis media - AOM • Middleearinflammation • Middleearinfection(s) I • Antibiotic(s) • Antimicrobial • Antibacterial • Amoxicillin • Analgesics • Placebo • Wait/Watch-and-see

10. MultipleResources

11. Electroniclibrarycatalogs Internet searchengines Professional databases

12. ElectronicLibraryCatalogs (1) NationalMedicalLibrary, Prague, Czech R. /Medvik http://www.medvik.cz Navigation, functions: SearchMedvik/ Advanced AllFields-- MeSH: otitis media Search Date/ descending ?MeSH= MedicalSubjectHeadings (thesaurus)

13. ElectronicLibraryCatalogs (2) NationalLibraryofMedicine, Bethesda, USA/LocatorPlus http://www.locatorplus.gov Navigation and functions: LocatorPlus / FindBooks …. Advanced Menu Search otitis media phrase/Title AND antibioticantibioticsanyof these/Title Search Sort results /Publishdatedescending Detailedview Ctrl+F/otitis/Hledej

14. ElectronicLibraryCatalogs (3) International Joint CatalogWorldcat http://www.worldcat.org Navigation, functions: AdvancedsearchTitle/ otitis media Keyword/ antibiotics Year/ 2000-2014 Content/ Thesis/Dissertation Search

15. SearchEngines http://www.google.comhttp://www.yahoo.comhttp://www.bing.com

16. MedicalWebsitesQuality eEurope 2002: Free access QualityCriteriaforHealthrelatedWebsites CommunicationfromtheCommission to theCouncil, theEuropeanParliament, theEconomic and SocialCommittee and theCommitteeoftheRegions

17. MedicalWebsitesQualityBasic Criteria • Transparency and Honesty • Authority • Privacy and data protection • Updatingofinformation • Accountability • Accessibility

18. INTERNETDeepSearchEngines : Scholar Google • http://www.scholar.google.com • Journalarticles • Cited by • Relatedarticles • Versions • Citační ohlasy Navigation and functions: AdvancedSearch Phrase: otitis media At least oneofthewords: antibioticantibioticsantimicrobialamoxicillin Occurrence: articletitle Date: 2009-2014

19. Professional MedicalDatabases : selection MEDLINE/PubMed • Bibliographic database with fulltext links • Free access DynaMed • Point-of-care EBP knowledgebase • Institutional licence, IP-recognition UpToDate • EBP knowledgebase • Institutional licence, IP-recognition COCHRANE LIBRARY • Systematicreviews • Institutional licence, IP-recognition

20. MEDLINE/PubMed http://www.pubmed.gov Advanced Search

21. MEDLINE/PubMed „Gold Standard“forniomedical and healthsaciences Coverage: • >5000journalspublished in the USA a 80othercountries • > 23 mill.records, retro since1950 AllrecordshaveEnglishabstractsirrespectiveoforiginallanguage MEDLINE/PubMedwww.pubmed.gov • Summary + abstract + MeSHterms • Fulltext linksfromproviders • LinkOut– More Resources • Free • Licence/subscription • Absent /somearchivalmaterials

22. SearchToolsBooleanOperatorsAND, OR, NOT Documentsmustcontainat least two(or more) searchterms • otitis media AND antibiotics Documentsmustcontainany(orall) ofsearchterms • otitis media OR middleearinflammation Documentsmust not containsearchterms • otitis media NOT surgery

23. PubMed: SearchStrategy URL: http://www.pubmed.gov --- Advanced SearchBuilderfunctions BooleanoperatorsOR, AND, NOT Truncation/wildcards* Step #1 Title: otitis media (search term occurs in articletitle) OR Title/abstract: middleearinflammation(search term occursin articletitleorabstract) Add to History Step #2 Title: antibiotic* (searchterm occurs in articletitle) OR Title/abstract: antimicrobial* (search term occurs in articletitleorabstract) Add to History Step #3 History #1 AND #2 Search Show additionalfilters: Ages – Show: Infant birth-23 months

24. PubMed : Results • Summary • Abstract • Relatedarticles • Send to : • File • E-mail(library fulltext services) • Articletypes, MeSHTerms (MedicalSubjectHeadings) • Linkout– more resources • Free fulltext • Providers, publishers – fee, subscription • Absent

25. Sendto == Email REMINDER: Additionaltext mustcontainyourcontact.

26. Knowledgebasesfor evidence-basedpractice(evidence basedmedicine – EBM) DynaMed UpToDate

27. http://search.epnet.com

28. Navigation and functions http://search.epnet.com • IP-recognitionwithin Palacký University network • Remoteaccess • A point-of-care reference tool with clinically-organized summaries for more than 3,200 topics, which monitors the content of medical journals and systematic evidence review databases through journal review services. Each article is evaluated for clinical relevance and scientific validity, and the new evidence is then integrated with existing content, with overall conclusions being drawn from the best available evidence. • Example: otitis media antibioticsSearch • Choose a summaryfromthe list • Open theselectedtopic • Searchwithintext -keywordsearch • „Levelsof evidence“ – validity • Referencesincludingreviews and guidelines

29. Result : Acute otitis media (AOM) Treatmentoverview

30. www.uptodate.com/online

31. Navigation and functions: http://www.uptodate.com/online • IP-recognitionwithin Palacký University and TeachingHospitalnetworks • Remoteaccess Evidence-basedclinicalsummaries, regularlyuptodated >8,000 criticallyxappraisedtopics • 14 specialties • >80 000 pages(text, graphics, PubMedlinks) • Patientinformation • Quarterlyupdates

32. New Search: otitis media antibiotics Search

33. Results: Acute otitis media in children: Treatment

34. FindAnswer to OurResearchQuestion Summary and Recommendations Thechoiceofinitialtreatmentwithantibioticsorobservationdependsupon theageofthechild and the laterality and severityofillness: • Werecommendthatchildrenwith AOM who are <6 monthsbetreatedwithantibiotics • Wesuggestthatchildrenwith AOM who are betweensixmonths and twoyearsbetreatedwithantibiotics ATD. Boy, 2 yearsold, acute otitis media

35. Discussion, exercise Searchforthesametopic in the COCHRANE LIBRARY a database ofsystematicreviews. • Free access to structuresasbtracts • Fulltext fee-based.

36. COCHRANE LIBRARY http://www.cochrane.org