Risk Ratio for Coronary Heart Disease Mortality in 59 Randomized Controlled Trials of Cholesterol-Lo...
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Statins 0.69 (0.59-0.80) n=13 (16,228/11,279) n-3 fatty acids 0.44 (0.18-1.07) - PowerPoint PPT Presentation


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Risk Ratio for Coronary Heart Disease Mortality in 59 Randomized Controlled Trials of Cholesterol-Lowering Interventions. Risk Ratio % 95% CI. Benefit. Harm. Statins 0.69 (0.59-0.80) n=13 (16,228/11,279) n-3 fatty acids 0.44 (0.18-1.07) n=3 (1,348/1,349) Fibrates 0.98 (0.78-1.24)

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Risk Ratio for Coronary Heart Disease Mortality in 59 Randomized Controlled Trials of Cholesterol-Lowering Interventions

Risk Ratio % 95% CI

Benefit

Harm

Statins 0.69 (0.59-0.80)

n=13 (16,228/11,279)

n-3 fatty acids 0.44 (0.18-1.07)

n=3 (1,348/1,349)

Fibrates 0.98 (0.78-1.24)

n=12 (9,873/11,496)

Resins 0.71 (0.51-0.99)

n=8 (3,280/3,257

Hormones 1.04 (0.93-1.17)

n=8 (4,516/9,039)

Niacin acids 0.85 (0.83-1.10)

n=2 (1,196/2,932)

Diet 0.91 (0.82-1.01)

n=16 (48,481/59,042)

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1.0

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Arterioscler Thromb Vasc Biol. 1999;19:187-195


Risk Ratio for Overall Mortality in 59 Randomized Controlled Trials of Cholesterol-Lowering Interventions

Risk Ratio % 95% CI

Benefit

Harm

Statins 0.79 (0.71-0.89)

n=13 (16,228/11,279)

n-3 fatty acids 0.66 (0.53-0.88)

n=3 (1,348/1,349)

Fibrates 1.06 (0.78-1.48)

n=12 (9,873/11,496)

Resins 0.85 (0.66-1.08)

n=8 (3,280/3,257

Hormones 1.09 (1.00-1.20)

n=8 (4,516/9,039)

Niacin acids 0.96 (0.86-1.08)

n=2 (1,196/2,932)

Diet 0.97 (0.81-1.15)

n=16 (48,441/59,042)

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1.0

2

Arterioscler Thromb Vasc Biol. 1999;19:187-195


Risk Ratio for Mortality Other Than From CHD in 59 Randomized Controlled Trials of Cholesterol-Lowering Interventions

Risk Ratio % 95% CI

Benefit

Harm

Statins 0.97 (0.81-1.16)

n=13 (16,228/11,279)

n-3 fatty acids 1.16 (0.63-2.12)

n=3 (1,348/1,349)

Fibrates 1.16 (0.63-2.12)

n=12 (9,873/11,496)

Resins 1.07 (0.74-1.55)

n=8 (3,280/3,257

Hormones 1.29 (1.08-1.57)

n=8 (4,516/9,039)

Niacin acids 0.99 (0.76-1.29)

n=2 (1,196/2,932)

Diet 1.00 (0.95-1.05)

n=16 (48,481/59,042)

.6

.7

.8

.9

1.0

2

3

Arterioscler Thromb Vasc Biol. 1999;19:187-195


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