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Kondensation. H 2 O. CoA -SH. Oxalacetat. Acetyl-CoA. Citrat. 1. Oxidative Decarboxylierung. NAD +. NADH + H +. CO 2. Isocitrat. - Ketoglutarat. 2. Oxidative Decarboxylierung. NAD +. NADH + H +. CoA -SH. CO 2. Succinyl-CoA. - Ketoglutarat. Kondensation. C OO -. H 2 O.

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Kondensation
Kondensation

H2O

CoA-SH

Oxalacetat

Acetyl-CoA

Citrat


1 oxidative decarboxylierung
1. OxidativeDecarboxylierung

NAD+

NADH + H+

CO2

Isocitrat

-Ketoglutarat


2 oxidative decarboxylierung
2. OxidativeDecarboxylierung

NAD+

NADH + H+

CoA-SH

CO2

Succinyl-CoA

-Ketoglutarat


Kondensation1
Kondensation

COO-

H2O

COO-

+

-OOC

CoA-SH

COO-

COO-

Oxalacetat

Acetyl-CoA

Citrat


Erste oxidative decarboxylierung
Erste oxidativeDecarboxylierung

COO-

COO-

NAD+

NADH + H+

-OOC

CO2

COO-

COO-

Isocitrat

-Ketoglutarat


Zweite oxidative decarboxylierung
Zweite oxidativeDecarboxylierung

COO-

NAD+

NADH + H+

CoA-SH

CO2

COO-

COO-

Succinyl-CoA

-Ketoglutarat