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水溶性维生素 PowerPoint PPT Presentation


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水溶性维生素. 水溶性维生素: VB 1 ( 硫胺素 ) VB 2 ( 核黄素 ) VB 6 ( 吡哆醇 ) VB 12 ( 氰钴胺素 ) VC( 抗坏血酸 ) 烟酸 ( 尼克酸 ) 叶酸、泛酸、胆碱 、生物素等。. 水溶性维生素的共同特点. (1) 化学组成除碳、氢、氧外尚有氮、 硫、钴等元素。 (2) 溶于水而不溶于脂肪及脂溶剂。 (3) 在满足了组织需要后,多余的将由 尿排出。 (4) 没有非功能性的单纯储存形式,在

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水溶性维生素

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4271230


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VB1()

VB2()

VB6()

VB12()

VC()

()


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(1)

(2)

(3)

(4)


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(5)

(

)

(6)

(7)

(8)


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B1

B12697

1897Eijkman


4271230

1911FunkLister(amine)(Vital-amine)


4271230

1926JansenDonathB1(aneurin)

1936WilliamsB1B1


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B1

B1100pH5120pH 3140 1pH>7


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121mg


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90-150g 0.6mg01mg


4271230

1 :

B1(ATP) TPP)B1 TPP-,


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2

B1B1


4271230

3 B1TPP(TTP)TTP

4.


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B1

1.

2.

3.


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B1

B1B1


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1.


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.


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2.:

3.

4.

25VB1


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5. )


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)

66ug

) TPP TPP

15


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VB1


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  • 30-40


4271230

B1


B 2 riboflavin

B2( Riboflavin)

19

1933(FAD)(FMN)B6


4271230

  • (FAD)FMN)

  • 240~(22800C27.50C100mL12mg


4271230


4271230

  • FMNFDAFMNFDA


4271230


4271230

  • CuZnFe


4271230

  • 60-70

  • (5120gL)


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  • 1


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2FDAFMNB6

3FDA(GSSG)(GSH)

4P450


4271230

FAD


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  • 1.


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  • 2.

  • 3.


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  • 4.

  • BB6


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4271230


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  • 60ms116m9


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FMNFAD1135


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5.

0.5mg1000kcal1.4mg

1.2mg


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B2


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B6

  • Gyorgy1934B61938B61939

  • B6B6B6


4271230

  • B62-3--5-(PN),(PL)(PM)B6


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  • B6

  • pHB6

  • 4-

  • D6


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  • B6 B6


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  • B6

  • D6 B6


4271230

VB6PLP

VB6

VB6PLP100

VB65.

PLPPLP


4271230

  • VB6B12

  • ,PLP

    B6 B6D6

    B6 PLP

  • 5-7

    B6(CHD)


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  • D6B6

  • 2050PL

  • B6


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  • PLP


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  • VB6


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B6

  • B6(

  • )()


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  • PPB5

  • 1867Huber

  • 70

  • 1913Funk

  • 20


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  • 191320Goldberger

  • 1937Elvehjem()


4271230

  • 251g60ml80mllg1m11.5ml


4271230

1(CoINADI)(CoNADP )


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2 : (glucosetolerancefactorGTF)

3 :

-


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  • (dermatitis)(diarrhea)(depression)D3D'


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1


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  • 2

  • 3


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NAD+NADP +l00ml128338gl00ml20-100g


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  • (NE)

  • 60mg1mg

    (mgNE)(mg)+160(mg)


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  • 12N1- 2

  • 3

  • ()NADHNADPH


4271230

  • 301000msd


4271230

  • 1000kcalmg


4271230

  • 80-90


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  • ()


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  • (folic acid)B

  • 1941Mitchell

  • 1998(FDA1.4mg/kg)


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  • 785678


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  • 1005090


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  • 60 g/d60 g

  • C


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  • DNARNA


4271230


4271230


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  • (50gd)20


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B12

  • B12(1F)


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  • B12B12a-56 B12


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  • B12 B12(IF) TcB12


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  • B122-3mg

  • B12B126B12B122-3


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  • B12B12B12

  • 1

  • 2A


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  • 1 B12B12B12


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B12

B125510DNA


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  • B6B12B12


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B12


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()B12

()(B12)

)

()B12


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  • 100gB12


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  • B12B12


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  • B3,.

  • 1931Ringrose

  • 1933Williams

  • 1939Williams

  • 1950CoA


4271230

  • (26)

    pH5-7


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  • A4060

  • A

  • ([I15)CO2


4271230

  • A AAAAA


4271230

  • AA (HSCoA)3 .


4271230


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  • 100


4271230


4271230

  • AI


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4271230

  • HR

  • 40

  • 1901Wildiem19161927BatemanBoas

  • 19333llisonR


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  • 1936KR1Tonnis1937

  • GyorgyH

  • 1940GyorgyRH


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  • 1942du Vigneaud

  • 1943


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  • 8


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  • -

  • CO2

  • I


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  • 106


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4271230


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  • FNBA1


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  • (choline)1849Strecker

  • 18621866

  • 1941Devigneaud

  • 1940SuraGyorgy Goldblatt


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  • 2030


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  • (-)HOCH2CH2N(CH3)3


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4271230


4271230


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  • 10


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  • 12-171630()()()


4271230

  • (apoptosls)


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3()


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  • (EAR)(RNl)

  • FNBA1A1500mgd


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4271230

C

  • C1550450C

  • 1497Vascvo da Gama160100

  • 1740Anson61955451051


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  • 1516

  • 1747(JLind)1795


4271230

  • 1928AlbertSzent-GyisrgyiC6H8O6

  • 1932KingWaugh

  • 1933Howo~hHirstCReichsteinCC


4271230

  • C6HC

  • LD2


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  • CC


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  • C

  • C

  • C


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  • (1)(2)(3)4)

  • PbHgCdAsC

  • CN


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  • CNADH


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  • C300mg


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  • 1 C

  • 47

  • 61


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  • 2


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  • 3


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  • 4 C


4271230

  • CC-2-


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  • c

  • 1C CCC 2C C4


4271230

  • CC 2g1gC


4271230

CCCC


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