Bioinformatics. Ayesha M. Khan 22 Feb, 2012. Flowchart of sequence data from labs and literature to primary sequence database and subsequent secondary databases. Secondary Sequence Database Protein Domains & Families Metabolic Pathways
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Ayesha M. Khan
22 Feb, 2012
Secondary Sequence Database
Protein Domains & Families
e.g. RefSeq and Conserved Domain Database (CDD) within NCBI
Primary Sequence Database
Amino AcidNucleic Acid
e.g. GenBank, EMBL, DDBJ
SwissProt and PIR
Started in 1986-University of Geneva and EMBL
It is now maintained by Swiss Institute of Bioinformatics (SIB) and EBI/EMBL
Started in 1996-Follows SWISS-PROT format and contains translations of coding sequences in EMBL.
It also provides: synthetic sequences, short amino acid fragments, and codons that do not encode real proteins.