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INFECTIOUS COMPLICATIONS AFTER VACCINATION

INFECTIOUS COMPLICATIONS AFTER VACCINATION. Dr Alireza Nateghian Associate professor of Pediatrics and Pediatric infectious diseases NATIONAL COMMITTEE FOR AEFIs INVESTIGATION. Classification of AEFIs. Vaccine reaction Program error Coincidental Injection reaction unknown.

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INFECTIOUS COMPLICATIONS AFTER VACCINATION

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  1. INFECTIOUS COMPLICATIONS AFTER VACCINATION Dr AlirezaNateghian Associate professor of Pediatrics and Pediatric infectious diseases NATIONAL COMMITTEE FOR AEFIs INVESTIGATION

  2. Classification of AEFIs • Vaccine reaction • Program error • Coincidental • Injection reaction • unknown

  3. Vaccine reactions • Due to vaccine nature • Mild reactions • Severe reactions

  4. MILD(USUAL) REACTIONS 1.immunologic response to vaccine: - local reaction(BCG:90%,HEPATITIS B:5-15%, MMR:10% ,T/DT/Td:10% ,Pertussis:50%), increases with repeated dose up to 50-85% - systemic response: • FEVER(Hepetitis B:1-6% ,MMR:5-15% ,OPV:1%,T/TD/Td:10%,Pertussis:50%) • Systemic reactions:irritability,fatigue,loss of appetite,headache,diarrhea,bodypain,mildmeasles,mumps,rubellaartralgia)(MMR:5% ,OPV:<1%,T/TD/Td:25%,pertussis:50-60%) 2.adjuants,perservatives…

  5. Rare(severe) reactions

  6. Program errors

  7. TSS

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