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Seminar on The Role of Agricultural Biotechnologies for Production of Bioenergy in Developing Countries FAO Headquarters, Iran Room 12 October 2007.

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Areas of research and training undergoing at icgeb

Seminar on The Role of Agricultural Biotechnologies for Production of Bioenergy in Developing Countries

FAO Headquarters, Iran Room

12 October 2007


Areas of research and training undergoing at icgeb

"Broadly defined, biotechnology is the manipulation of living organisms to produce goods and services useful to human beings." (From: "Modifying Africa" of F. Wambugu).


Areas of research and training undergoing at icgeb

Microbial agro-industrial biotechnology stems from the traditional practices and products developed by farmers and their families for use on the farm or in the homestead.These practices can be improved greately by the correct implementation of genetic engineering

Ethical concerns: Modern biotechnology is often seen as unnatural, but in fact it relies on most of the same spontaneous processes occuring in nature and leading to improvement through selction

THE ICGEB, AT ITS LOCATION OF TRIESTE PROMOTES BASIC AND ADVANCED SCIENTIFIC TRAINING IN THE AREA OF MICROBIAL BIOTECHNOLOGY FOR ITS APPLICATIONS IN AGRO-INDUSTRY.AMONG THE ICGEB MEMBER COUNTRIES SEVERAL AFRICAN COUNTRIESARE ALREADY TAKING ADVANTAGE OF THEICGEB PROGRAMMES (http://www.icgeb.org)


Areas of research and training undergoing at icgeb

AREAS OF RESEARCH AND TRAINING UNDERGOING AT ICGEB:

Utilization of genetically selected yeast strains enriched for particular aminoacids (lysine, methionine) for animal feed, and for cellulose and hemicellulosa digestion. (Microbiology, Trieste)

Study of plant growth-promoting bacteria (Pseudomonads).

Development of insect and pesticide-resistant crops (N.D.)

Studies towards the production of stress (drought)-resistant plants (N.D.)


Areas of research and training undergoing at icgeb

  • Areas of Primary concern for Developing Countries

  • Epidemiology of food-related diseases and genetic susceptibilities

  • Impact of new technologies on food production

  • Chemical contaminants and pathogens

  • Safer production and healthier foodstuffs from agriculture

  • Animal feed and impact on human health

  • Environmental health risks


Areas of research and training undergoing at icgeb

ROLE OF TECHNOLOGY PARKS AND INCUBATORS

IN TECHNOLOGY TRANSFER

Successful experiences in creating technology parks/ incubators providing a basic infrastructure to transform ideas into products and services can serve as model for developing Countries.

For example, given the comparative advantage of diversified ethanol production in the world, particular emphasis could be focussed upon research and transformation of agricultural products in such technology parks.

It would also be advisable to set up technology parks near existing institutions to attract foreign contract research funds to perform applied research in situ.


Innovation for development

Innovation for Development

Science

Innovation

Socialneeds

Technology


Areas of research and training undergoing at icgeb

  • Food Safety and Health Risks

  • Background and Aims:

  • Assuring health and well-being of citizens

  • Food intake and environmental factors

  • Safer and health promoting foods

  • Controlled and integrated production systems

  • From farm to fork – consumer protection as the driver


Areas of research and training undergoing at icgeb

  • Epidemiology of food-related diseases and genetic susceptibility

  • - Diet, lifestyle and health

  • - Measuring dietary intake and risk assessment

  • - Influence of genetic variability


Areas of research and training undergoing at icgeb

  • Traceability

  • Chemical contaminants and pathogens

  • - Analysis and detection

  • - Improved prevention and measurement control

  • - Prion detection, mapping, transfer mechanisms

  • Safer production and healthier foodstuffs

  • - Conventional vs. organic vs. GMOs

  • - Improved animal welfare, husbandry and waste management

  • Animal feed and impact on human health

  • Environmental health risks


Areas of research and training undergoing at icgeb

Respiration (O2 + dispensable mitochondria, r+ , r-, r0) and Fermentation (anaerobic) convert sugars (hexoses): sucrose>fructose>glucose>maltose =CO2 + ethanol


Areas of research and training undergoing at icgeb

THE ICGEB MANDATE

To provide a Centre of excellence for research and training in genetic engineering and biotechnology addressed to developing countries


The structure

THE STRUCTURE

ICGEB IS ONE CENTRE, MADE OF TWO

COMPONENTS AND A NETWORK OF

AFFILIATED CENTRES

+

A NETWORK OF AFFILIATED CENTRES


Areas of research and training undergoing at icgeb

ICGEB: an intergovernmental organisation

67 Signatory States, 51 Member States, 2 Components: Trieste (Italy) - New Delhi (India) and a network of 35 Affiliated Centres


Areas of research and training undergoing at icgeb

NEW DELHI COMPONENT


Instruments of action

INSTRUMENTS OF ACTION

  • RESEARCH PROJECTS

  • LONG TERM TRAINING

  • SHORT TERM TRAINING

  • COLLABORATIVE RESEARCH PROGRAMME

  • COOPERATION WITH INDUSTRIAL SECTOR

  • SCIENTIFIC SERVICES

  • INSTITUTIONAL SERVICES


Summary of the activity of the icgeb 1988 2004

SUMMARY OF THE ACTIVITYOF THE ICGEB (1988-2004)

  • INTERNATIONAL PUBLICATIONS:1,220

  • LONG TERM FELLOWSHIPS:481 awarded; 797 MAN/YEARS

  • SHORT TERM TRAINING:5,826 persons trained

  • RESEARCH GRANTS: 232 awardedfor a total of US$ 12,163,781.00

  • PATENTS:30 filed

  • TECHNOLOGY TRANSFER

    AGREEMENTS:65 signed


Institutional activities

INSTITUTIONAL ACTIVITIES

COOPERATION AGREEMENT WITH THE UNITED NATIONS SECRETARIAT. UN AND ICGEB COOPERATE IN ACTIVITIES RELATED TO

  • SAFE AND SUSTAINABLE USE OF GENETIC ENGINEERING AND BIOTECHNOLOGY

  • PROTECTION OF BIODIVERSITY

  • BIOSAFETY AND RISK ASSESSMENT

  • IMPLEMENTATION OF ARTICLE X OF THE CONVENTION ON BIOLOGICAL DISARMAMENT


Areas of research and training undergoing at icgeb

MILLENIUM DEVELOPMENT

GOALS

“THE MILLENNIUM DEVELOPMENT GOALS MAY BE MORE EASILY MET WITH THE EXTENSIVE APPLICATION OF MODERN BIOTECHNOLOGY IN AGRICULTURE AND HEALTH”

(Report of the Secretary-General on “Impact of new biotechnologies, with particular attention to sustainable development, including food security, health and economic productivity”- 2003)


Areas of research and training undergoing at icgeb

GENERAL ASSEMBLY

RESOLUTION 58/200 - DECEMBER 2003

TAKES NOTE OF THE PROPOSAL OF THE SECRETARY GENERAL FOR AN INTEGRATED FRAMEWORK FOR BIOTECHNOLOGY DEVELOPMENT WITHIN THE UN SYSTEM AND THE NEED FOR STRENGTHENING CO-ORDINATION BETWEEN THESE RELEVANT ORGANISATIONS AND BODIES IN THE AREA OF BIOTECHNOLOGY


Areas of research and training undergoing at icgeb

INTER-AGENCY NETWORK FOR

CO-OPERATION IN BIOTECHNOLOGY

  • THE IANCB HAS BEEN ESTABLISHED IN MAY 2004 BY A CLUSTER OF INTERNATIONAL ORGANISATIONS IN ORDER TO:

  • ELABORATE JOINT STUDIES

  • STRENGTHEN THE ADVISORY ROLE IN BIOTECHNOLOGY OF THE UN

  • ASSESS THE IMPACT OF BIOTECHNOLOGY, IN DEVELOPING COUNTRIES

  • ESTABLISH A COMMON PORTAL FOCUSED ON BIOTECH-RELATED ACTIVITIES LINKED TO THE EXISTING SCIENCE AND TECHNOLOGY DEVELOPMENT NETWORK

  • ASSIST UNCTAD IN THE PREPARATION OF THE REPORT TO THE UNITED NATIONS GENERAL ASSEMBLY


Areas of research and training undergoing at icgeb

UN - ICGEB

Co-operation Agreement

April, 2001

“THE UNITED NATIONS AND THE INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY …CO-OPERATE IN ACTIVITIES RELATED TO THE SUSTAINABLE AND SAFE USE OF GENETIC ENGINEERING AND BIOTECHNOLOGY”

ACCORDINGLY, ICGEB IS PRESENTLY CHAIRING THE INTER-AGENCY NETWORK FOR CO-OPERATION IN BIOTECHNOLOGY AND IS TO PLAY A KEY ROLE IN ASSISTING UNCSTD IN THE PREPARATION OF THE REPORT TO THE GENERAL ASSEMBLY.


Schema del processo pilota

SCHEMA DEL PROCESSO PILOTA


Areas of research and training undergoing at icgeb

Modello di criomacinatore a scambio termico (CRISCAT)


Areas of research and training undergoing at icgeb

BioEthos

Project plan : 3 FASI

Fase 1: Ricerca Scientifica - ICGEB

Ingegnerizzazione dei ceppi di lievito

1.1 produzione ceppi transgenici per digerire la cellulosa in collaborazione con la Piattaforma Nazionale ITSusChem

1.2 ottimizzazione genomica per incrementare la percentuale di etanolo prodotto ad uso industriale; l’ottimizzazione verra’ realizzata tramite l’impiego di tecniche di miglioramento genomico in collaborazione con l’Universita’ di Oxford e grazie ad un sistema sviluppato e brevettato dal laboratorio YMG dell’ICGEB

Fase 2: Sviluppo - AREA/Talent Srl/ICGEB

Fermentazioni pilota

2.1 Verifica in laboratorio di digestione della cellulosa da materiale criomacerato (ICGEB), sviluppo di sistemi di controllo (Talent Srl)

2.2 sviluppo di impianto pilota con utilizzo di locali dell’AREA di ricerca per lo smaltimento di rifiuti chimici; come ricaduta vi sara’ la creazione di un Centro di Fermentazione (AREA)

Fase 3: Implementazione industriale -

Cartiere Burgo/Endesa/GasNatural

Trasferimento di frigorie

3.1 Utilizzo del freddo prodotto dai rigassificatori (Endesa/GasNatural) per la criomacerazione con conseguente digestione di cellulosa di scarto (Cartiere Burgo) e produzione industriale di BioEtanolo. In questa fase e’ presente il coinvolgimento di distributori petrolchimici.


Areas of research and training undergoing at icgeb

Tempistica di attuazione del progetto

Fasi

ICGEB

(Oxford)

ICGEB

ITSusChem

Ricerca

1.1 Nuovi lieviti

1.2 Ottimizzazione

Talent/

ICGEB/

Reg. FVG?

AREA/

Nuovi

Partners

Sviluppo

2.1 Verifiche

2.2 Imp. Pilota

Burgo/

Endesa/

GasNatural/

Db.Petrolchimici

Produzione

(Implementazione industriale)

3.1 Trasferimento frigorie

0 1 2 3 t(anni)


Areas of research and training undergoing at icgeb

DIAGRAMMA DI PROCESSO

MALIC

cippato

FASE 1

Pre-trattamento interno

Macinazione

meccanica

Macinazione

biogenica

Batteri & Lieviti

PAD

Acido

Vanillico


Areas of research and training undergoing at icgeb

  • Proposta di Progetto:

  • Produzione di bioetanolo con lieviti ingegnerizzati,

  • via fermentazione di derivati vegetali criomacerati

  • nella regione Friuli Venezia-Giulia

  • Responsabile: Prof. Carlo V. Bruschi

  • Head, Yeast Molecular Genetics Group ICGEB

  • AREA Science Park, Trieste

  • Department of Genetics and Developmental Biology

  • University of Salzburg, Austria

  • Collaboratori:

  • Dr. Sergio Stibelli

  • Talent S.r.l, Trieste

  • Paolo Mander

  • Sister - Liaison Office

  • AREA Science Park, Trieste

  • Dr. Valentina Tosato

  • Yeast Molecular Genetics Group, ICGEB

  • Dipartimento di Biofisica UNIGE &

  • Margburg University, Germany

    • Regione Friuli Venezia-Giulia

    • 23 Novembre, 2006


Areas of research and training undergoing at icgeb

Il sistema BIT per la bioenergia


Areas of research and training undergoing at icgeb

C


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