ECTOPIC PREGNANCY… acute congestion
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ECTOPIC PREGNANCY… acute congestion. … CH. CONGESTION…. “NUTMEG” LIVER. SUBARACHNOIDAL HEMORRHAGE… types of hemorrhages?. PARENCHYMAL HEMATOMA…. Lesion?... Mechanisms?... Clinical entities?. Lesion?... Mechanism?... Clinical entities?. Same questions…. WATERHOUSE-FRIDERICHSEN SYNDROME.

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ECTOPIC PREGNANCY… acute congestion


… CH. CONGESTION…

“NUTMEG” LIVER


SUBARACHNOIDAL HEMORRHAGE… types of hemorrhages?


PARENCHYMAL HEMATOMA…


Lesion?... Mechanisms?... Clinical entities?


Lesion?...

Mechanism?...

Clinical entities?


Same questions…


WATERHOUSE-FRIDERICHSEN SYNDROME


IDEM


THROMBOSIS: PATHOGENESIS: VIRCHOW’S TRIAD.


VEIN THROMBOSIS: Causes…


EMBOLIZATION,

PULMONARY

THROMBO-EMBOLISM


EMBOLISM: TYPES

  • FAT

Most likely

cause?


RED (HEMORRAGHIC) INFARCT

OVARIAN CYST W/TORSION & FURTHER INFARCT


WHITE (ANEMIC) INFARCT

  • SPLEEN


Fibrinoid thrombus

Causes, mechanisms…


GENETIC DISORDERS I

CATEGORIES OF MUTATIONS:

  • GENOME (vgr.Trisomies)

  • CHROMOSOME (vgr. Cri-du-chat)

  • GENE (vgr. Mendelian)


Organelle?... Process?


TAY-SACHS


NIEMANN-PICK


CHERRY-RED-SPOT

…BLINDNESS


VON-GIERKE

MC. ARDLE


Muchopolisaccharidosis


OCHRONOSIS… Serum abnormality… other affected tissues…transmission?


TYPE OF: Mutation, inheritance


IDEM


XANTHELASMAS


TWO LESIONS…


NF2

Which chr.

Affected?

MENINGIOMA


Type of cyto-

genetic alteration


Idem,,, Best other diagnostic test?


bcr

9:22

rearrengement

abl

Residual abl


Risk factor?... Most common phenotypical alterations…


Phenotypical alterations…


Idem…


Idem…


Idem…


COMMON MULTIFACTORIAL DISORDERS

3 major characteristics…


ANENCEPHALY


Hirschsprung disease: Congenital aganglionic megacolon


Elongated face & large mandibule

Large, everted ears

Mild strabismus

Hyperelastic joints, high palated & mitral valve prolapse

Mental retardation

Macro-orchidism


MUTATIONS IN MITOCHONDRIAL GENES

LEBER HEREDITARY OPTIC NEUROPATHY (LHON)


IDEM:

PEDIGREE


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