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CITR Annual Report Exhibits

CITR Annual Report Exhibits.

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CITR Annual Report Exhibits

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  1. CITR Annual Report Exhibits Collaborative Islet Transplant Registry (CITR) 2009 Annual ReportExhibitsPrepared by:CITR Coordinating CenterThe EMMES CorporationRockville, MDSponsored by:National Institute of Diabetes & Digestive & Kidney DiseasesNational Institutes of HealthJuvenile Diabetes Research FoundationDatafile Closure: April 1, 2009

  2. Insulin Dependent 46.5 Insulin Independent 17.6 No Graft Function 20.8 No Data 15.0 Insulin Dependent 37.9 Insulin Independent 25.9 No Graft Function 21.6 No Data 14.5

  3. Chapter 1: Islet Transplant Activity Chapter 2: Recipient and Donor Characteristics Chapter 3: Pancreas Procurement, Islet Processing, and Infusion Characteristics Chapter 4: Immunosuppression and Other Medications Chapter 5: Graft Function Chapter 6: Liver, Kidney, Lipid, and PRA Effects Chapter 7: Adverse Events Chapter 8: Registry Data Quality Review CITR Coordinating Center CITR Committees Table of Contents

  4. Chapter 1: Islet Transplant Activity

  5. Islet Transplant Centers Reporting Data to CITR:Participating North American Centers 1999-2008 A - CITR Centers with at least one islet allograft infusion procedure conducted in 2008C - CITR Centers with no islet allograft infusions in 2008D - CITR Coordinating Center

  6. Islet Transplant Centers Reporting Data to CITRParticipating European Centers 1999-2008 A - CITR Centers with at least one islet allograft infusion procedure conducted in 2008 B - CITR Centers with data reports pending

  7. Islet Transplant Centers Reporting Data to CITRParticipating Australian Centers 1999-2008 A - CITR Centers with at least one islet allograft infusion procedure conducted in 2008 C - CITR Centers with no islet allograft infusions in 2008

  8. Number of Islet Transplantation Centers Performing Islet Allografts per Year and Number with Data Entered in CITR Database All North American Islet Transplant Centers 1999-2008

  9. Total Number of Islet Allograft Recipients, Recipients at CITR-Participating Centers, and Recipients with Detailed Data Reported to CITR by Year of First Islet Allograft InfusionAll North American Islet Transplant Centers 1999-2008 The Islet Transplant Summary (ITS) questionnaire is completed by all North American Islet Transplant Programs regardless of their participation in the Registry. Of 46 North American islet transplant programs polled, all have provided this information through 2007.

  10. Total Number of Islet Allograft Recipients and Recipients with Detailed Data Reported to CITR by Year of First Islet Allograft InfusionCITR-Participating European and Australian JDRF Centers 1999-2008

  11. Total Number of Islet Allograft Infusion Procedures Performed andNumber with Data Reported to CITRCITR-Participating North American Islet Transplant Centers 1999-2008

  12. Total Number of Islet Allograft Infusion Procedures Performed and Number with Data Reported to CITRCITR-Participating European and Australian JDRF Centers 1999-2008

  13. Total Number (N=828) of Islet Allograft Infusion Procedures Conducted andEntered in CITR Database, by Year and Infusion Procedure NumberCITR-Participating North American and JDRF Centers, 1999-2008

  14. Number (N=828) of Islet Allograft Infusion Procedures Per Recipient:CITR-Participating North American and JDRF Centers, 1999-2008

  15. Total Number (N=905) of Deceased Donors per Islet Allograft Infusion ProcedureCITR-Participating North American and JDRF Centers, 1999-2008

  16. Islet Alone 347 Islet After Kidney 65 Islet Alone and Islet After Kidney RecipientsCITR-Participating North American and JDRF Centers, 1999-2008

  17. Chapter 2: Recipient and Donor Characteristics

  18. Recipient Demographics

  19. Transplant Recipient Primary Funding InformationCITR-Participating US Centers

  20. Recipient Characteristics at First Infusion

  21. Recipient Diabetes Characteristics at First Infusion

  22. Recipient Autoantibodies at First Infusion

  23. Recipient Infectious Disease Testing at First Infusion

  24. Recipient Characteristics at First Infusion by Total Number of Infusions Received

  25. Recipient Demographics and Characteristics at First Infusionby Total Number of Infusions Received

  26. Recipient Laboratory Values at First Infusion

  27. Donor DemographicsAll Allograft Donors

  28. Donor CharacteristicsAll Allograft Donors

  29. Donor CharacteristicsAll Allograft Donors (continued)

  30. Characteristics of Organ Procurement and Donor Cause of DeathAll Allograft Donors

  31. Treatments Given to Donor During HospitalizationAll Allograft Donors

  32. Treatments Given to Donor During HospitalizationAll Allograft Donors(continued)

  33. Donor SerologyAll Allograft Donors

  34. Donor Laboratory DataAll Allograft Donors

  35. Organ Crossmatch ResultsAll Allograft Donors

  36. Chapter 3: Pancreas Procurement, Islet processing and Infusion Characteristics

  37. Pancreas Procurement and Islet Processing

  38. Pancreas Procurement and Islet Processing (continued)

  39. Cold Ischemia Information

  40. Islet Equivalents and Timing of Count

  41. Islet Product Characterization

  42. Islet Product and Infusion Characteristics by Infusion Sequence

  43. Univariate Analysis of Islet Characteristicsby Pancreas Preservation Method

  44. Significant Relationships (p<0.05) between Islet Outcomes and Categorical PredictorsUnivariate Analysis

  45. Significant Relationships (p<0.05) between Islet Outcomes and Categorical PredictorsUnivariate Analysis (continued)

  46. Significant Relationships (p<0.05) between Islet Outcomes and Categorical PredictorsUnivariate Analysis (continued)

  47. Significant Relationships (p<0.05) between Islet Outcomes and Categorical PredictorsUnivariate Analysis (continued)

  48. Univariate Correlation of Islet Characteristics with Donor, Recovery, and Processing Characteristics

  49. Univariate Correlation of Islet Characteristics with Donor, Recovery, and Processing Characteristics (continued)

  50. Univariate Correlation of Islet Characteristics with Donor, Recovery, and Processing Characteristics (continued)

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