Association of melanocortin 4 receptor (MC4R) polymorphism with body composition and carcass traits ...
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Association of melanocortin 4 receptor (MC4R) polymorphism with body composition and carcass traits of commercial pigs in Thailand. body composition carcass traits. EBV. genotype. Selection. Required less time to apply.

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Body composition carcass traits

Association of melanocortin 4 receptor (MC4R) polymorphism with body composition and carcass traits of commercial pigs in Thailand

body composition

carcass traits

EBV

genotype

Selection

Required less time to apply


Body composition carcass traits

Association of melanocortin 4 receptor (MC4R) polymorphism with body composition and carcass traits of commercial pigs in Thailand

Traits for study

BL, body length (cm)

SL, shoulder length (cm)

HL, ham length (cm)

RL, rump length

%Lean, percent lean

aLAM, loin eye area muscle adjust at 104 kg (kg)

D104, day during birth to body weight at 104 kg (day)

aBF, backfat thickness adjust at 104 kg (cm)

back


Body composition carcass traits

Association of melanocortin 4 receptor (MC4R) polymorphism with body composition and carcass traits of commercial pigs in Thailand

digested by the restriction endonucleaseTaq I

AA

AA

AG

AG

GG

483 bp

500 bp

407 bp

76 bp

Figure 2 RFLP fingerprint on 2% agarose.

AA = 483 bp

AG = 483,407 and 76,

GG = 407,76


Body composition carcass traits

Table1. Heritability of the traits (diagonal), genetic correlation (above diagonal) and phenotypic correlation (belowdiagonal)

rg

Low to Moderate

Genetic response slow

1 BL, body length (cm); SL, shoulder length (cm); RL, rump length; HL, ham length (cm); aBF, backfat thickness adjust at 104 kg (cm); aLAM, loin eye area muscle adjust at 104 kg (kg); %Lean, percent lean; D104, day during birth to body weight at 104 kg (day).


Conclusions

Association of melanocortin 4 receptor (MC4R) polymorphism with body composition and carcass traits of commercial pigs in Thailand

Conclusions

Slow

h2

Low

1) Body composition

and D104

year

2) Body composition

rg

Low to Moderate

3) Polymorphism of MC4R may not be appropriate to use as candidate gene in this populations

- to confirm the result, many sample must be included


Body composition carcass traits

Introduction

  • Good meat texture

  • Low cholesterol

  • Good taste

  • Price higher 2-3 times

Thai Native Chickens

Broiler

?

?

?

Low growth rate

Improve growth traits

Growth traits

Candidate genes approach

(Wattanachant et al., 2004; Jaturasitha et al., 2008)


Body composition carcass traits

Materials and methods

(60 chickens/breed)

Pradoo Hang Dam

Chee

Data

Body Weight

(0, 4, 8, 12, 16 Wks)

Average Daily Gain (ADG)

(0- 4, 0-8, 0-12, 0-16 Wks)


Body composition carcass traits

Results and Discussion

Marker- traits Analysis

IGFBP2

IGF-I

cGH

GHSR

Not Associated

T>C

A>C

G>A

C>T

5’ UTR

Intron1

Intron3

Intron2

Not Associated

EBV data

Pradoo Hang Dam

Chee


Body composition carcass traits

Conclusions

Not Associated

Chee

Pradoo Hang Dam

IGF-I

cGH

marker-assisted selection

Improve growth traits


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