Welcome to the BioSeal CVC Powder Application Computer-Based Learning Module CBL Who should take this CBL Any clinici

2. It will take approximately 20 minutes to navigate through this CBL. Click the links below to jump to selected �chapters� in the course. Introduction How Does BioSeal CVC Powder Work? Hospital Uses of BioSeal CVC Powder Protocol for CVCs Application Tips More Information on BioSeal CVC Summary References

3. Introduction Describe BioSeal CVC Powder Describe the mechanism of action of BioSeal CVC Powder Discuss the benefits of BioSeal CVC Powder usage Explain the many hospital uses of BioSeal CVC Powder Learn protocol for applying BioSeal CVC Powder List powder application tips Learn how to find more information on the product and how to order BioSeal CVC Powder

4. Introduction A topical powder that forms an occlusive seal to stop the flow of blood and exudates from a wound and keep microbes from entering the site. A mixture of a hydrophilic polymer and potassium ferrate. A brown powder. Not a vasoconstrictor or a cauterizing agent. Non-systemic, non-toxic and it is not biologically derived.

5. How Does BioSeal CVC Work? BioSeal CVC Powder creates a seal or barrier to stop the flow of blood or exudates. The mechanism of action is a simultaneous two step action: The polymer rapidly dehydrates the blood and absorbs exudates. The potassium ferrate component agglomerates the blood solids creating an occlusive barrier.

6. How Does BioSeal CVC Work?

7. How Does BioSeal CVC Work?

8. Hospital Uses of BioSeal CVC

9. How Does BioSeal CVC Work? The ingredients of BioSeal CVC Powder are: A. An oxidized cellulose gauze B. A hydrophilic polymer and potassium ferrate C. A calcium alginate wound dressing D. Chitosan and potassium Place the pointer over the desired answer and click the left mouse button for immediate feedback.

10. How Does BioSeal CVC Work? A characteristic or benefit of the �BioSeal� is: A. It stops bleeding and absorbs exudates. B. It provides a barrier that allows nothing in, nothing out. C. It creates a hostile environment to inhibit microbial activity. D. All of the above. Place the pointer over the desired answer and click the left mouse button for immediate feedback.

11. Protocol for Catheter Insertion Insert and secure line per protocol. If gloves are wet with blood or fluids, clean them with sterile saline and dry them with gauze to prevent BioSeal CVC Powder from sticking to gloves. For Horizontal Surfaces: Pour powder to completely cover the site (create a small pile). Use of Powder Containment Device (PCD) is optional. For Vertical Surfaces: Place PCD around site, fill the PCD with powder. Apply continuous firm pressure directly over powder with clean, dry gloved fingers for 2 minutes to form the �BioSeal� and achieve hemostasis. For anticoagulated patients or larger Fr sizes, longer holding times may be required. Cover site with transparent dressing. Press and form transparent dressing around powder to help contain it around the access site. Apply BioSeal CVC sticker on top of transparent dressing without obstructing view of site.

12. Protocol for Dressing Changes Remove transparent dressing from site. Most of powder will come off with the dressing. Gently remove excess powder with dry sterile gauze. Clean site per protocol. Do not remove the BioSeal. The seal is an integral part of physically preventing microbial colonization down the external surface of the line. Aggressive scrubbing is not recommended as it will damage the seal. Observe site for tissue impressions or skin irritation. Apply more powder if bleeding/oozing occur during dressing change. Reapply transparent dressing per hospital protocol.

13. Protocol If pull back is necessary, brush away excess powder and then use chlorhexidine (or sterile saline) to loosen the �BioSeal�. (The seal must be broken before the catheter can be pulled back.) After pull back, repeat BioSeal CVC Powder application steps.

14. Protocol for PICC Line Discontinuation Remove transparent dressing from site. Brush away any excess powder, remove �BioSeal� with chlorhexidine (or sterile saline) as needed and gently remove line. You may feel an initial �tug� as the seal is broken. Apply BioSeal CVC Powder if bleeding occurs. Dress site per team protocol.

15. Protocols If gloves are wet with blood or other fluids, clean them with sterile saline and dry them with gauze to prevent BioSeal CVC Powder from sticking to gloves. True False Place the pointer over the desired answer and click the left mouse button for immediate feedback.

16. Protocols For dressing changes you should do which of the following: A. After removing transparent dressing, remove excess powder with your fingers. B. Remove the "BioSeal" if it is adhered to the line. C. Use chlorhexidine to lightly clean the area. Do not remove seal. D. Scrub aggressively on top of and around the line with chlorhexidine. Place the pointer over the desired answer and click the left mouse button for immediate feedback.

17. Completely cover site with powder. Apply firm, continuous pressure for two minutes directly over site with dry gloved fingers or non-adherent dressing to form the protective seal and achieve hemostasis. Leave seal over site; it will fall off naturally on its own, or if needed, may be removed with sterile technique.

18. Don�t hold pressure over BioSeal CVC Powder with gauze to avoid tearing the seal. Don�t check for hemostasis before the recommended holding time. This could disturb the seal formation. Don�t use BioSeal for internal bleeding as it is not biodegradable. Note: Upon application, a temporary warming or sensation may be felt when holding pressure over the powder.

19. Application Tips When applying BioSeal CVC Powder following line insertion, you should check for hemostasis before the recommended holding time of two minutes. True False Place the pointer over the desired answer and click the left mouse button for immediate feedback.

20. Application Tips Which of the following should not be used to hold pressure over BioSeal CVC Powder? A. Non-adherent dressing B. Dry, gloved fingers C. Gauze D. All of the above Place the pointer over the desired answer and click the left mouse button for immediate feedback.

21. More Information on BioSeal CVC There are resources available to educate both patients and clinicians about BioSeal CVC Powder. These resources include: Instructions for Patients and Medical Staff Posters Protocol sheets These resources are available at www.biosealcvc.com.

22. More Information on BioSeal CVC Call Biolife at 800-722-7559 for more information.

23. This CBL course has focused on: Uses of BioSeal CVC Powder in a hospital setting The components and mechanism of action of BioSeal CVC Powder Benefits of BioSeal CVC usage Protocols for applying BioSeal CVC Powder Powder application tips How to find more information on the product and how to order BioSeal CVC Powder Summary

24. Wang DS, Chu LF, Olson SE, Miller FJ,� Valji K, Wong WH, Rose SC, Austin M, Kuo MD. Comparative Evaluation of Noninvasive Compression Adjuncts for Hemostasis in Percutaneous Arterial, Venous, and Arteriovenous Dialysis Access Procedures.� J Vasc Interv Radiol 2008; 19: 72-79. Photos are the property of Biolife, LLC. References/Credits

25. We hope this Computer Based Learning course has been both informative and helpful. Feel free to review the screens of this course until you are confident about your knowledge of the material presented. Exit

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