R etrolental fibroplasia
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R etrolental Fibroplasia. Retinopathy of Prematurity Disturbance in the retinal vascularization in premature infants May be acute or chronic Usually bilateral, often asymmetric Causative role of supplemental oxygen. R etrolental Fibroplasia. Major risk factors Decreasing gestational age

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R etrolental Fibroplasia

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R etrolental fibroplasia

RetrolentalFibroplasia

  • Retinopathy of Prematurity

  • Disturbance in the retinal vascularization in premature infants

  • May be acute or chronic

  • Usually bilateral, often asymmetric

  • Causative role of supplemental oxygen


R etrolental fibroplasia1

RetrolentalFibroplasia

  • Major risk factors

    • Decreasing gestational age

    • Decreasing birth weight

  • Other associated risk factors

    • Acidosis

    • Apnea

    • PDA

    • Septicemia

    • Blood transfusions

    • Intraventricularhemorrhage


Retrolental fibroplasia clinical manifestations

RetrolentalFibroplasiaClinical Manifestations

Reference: Nelson Textbook of Pediatrics. 18th Edition. 2007.


Retrolental fibroplasia clinical findings

RetrolentalFibroplasiaClinical Findings

Reference: Nelson Textbook of Pediatrics. 18th Edition. 2007.


R etrolental fibroplasia2

RetrolentalFibroplasia


R etrolental fibroplasia

Stage 1 ROP

Stage 2 ROP

Stage 3 ROP


R etrolental fibroplasia

Stage 4 ROP

Stage 5 ROP


R etrolental fibroplasia

Stage 5 ROP


Retrolental fibroplasia diagnosis

RetrolentalFibroplasiaDiagnosis

  • Recommendations

    • Systematic serial ophthalmologic examinations of infants at risk

    • Infants weighing <1500g at birth

    • Infants born before 31 weeks AOG

    • Infants weighing >1500g at birth who have an unstable clinical course

Reference: Nelson Textbook of Pediatrics. 18th Edition. 2007.


Retrolental fibroplasia diagnosis1

RetrolentalFibroplasiaDiagnosis

  • Recommendations

    • Initial examination should be performed at 4th to 6th week of chronological age

    • ROP is diagnosed most often at 32nd to 44th week after conception.

    • Screening should continue until the retina is fully vascularized, until the changes of ROP have undergone spontaneous resolution, or until appropriate treatment has been given.

Reference: Nelson Textbook of Pediatrics. 18th Edition. 2007.


Retrolental fibroplasia treatment

RetrolentalFibroplasiaTreatment

  • Early Treatment of Retinopathy of Prematurity Study

    • Recommends treatment for infants with Stage 2 disease with vascular tortuosity and engorgement

  • Laser – treatment modality of choice

  • Vitrectomy and lensectomy in cicatricial disease

References: Nelson Textbook of Pediatrics. 18th Edition. 2007. Vaughan & Asbury’s General Ophthalmology 17th Edition. 2008.


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