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Prions_Stanley B. Prusiner. Wen-Chun Shaw BTC 575 052 SCIENTIFIC DISCOVERY  Dr. Vankley. Stanley B. Prusiner. The Nobel Prize in Physiology or Medicine 1997 For the discovery of "Prions - a new biological principle of infection". Background. Stanley B. Prusiner. Born May 28, 1942

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Prions stanley b prusiner

Prions_Stanley B. Prusiner

Wen-Chun Shaw

BTC 575 052 SCIENTIFIC DISCOVERY 

Dr. Vankley


Stanley b prusiner
Stanley B. Prusiner

The Nobel Prize in Physiology or Medicine 1997

For the discovery of "Prions - a new biological principle of infection".



Stanley b prusiner1
Stanley B. Prusiner

  • Born May 28, 1942

  • Chemistry, University of Pennsylvania(1964)

  • M.D., University of Pennsylvania, School of Medicine (1968)

  • Internship in Medicine, UCSF

  • (1968-69)

  • Residency in Neurology, UCSF(1972-74)




Prions

Prions School of medicine, San Francisco, CA 94143-0518, USA





Slow virus
Slow virus and strong degradative enzymes.

Scarpie virus(sheep)

Kuru(highlander in New Guinea)

CJD


Diseases
Diseases and strong degradative enzymes.



  • Humans might be infected by prions in 2 ways: prions)

  • Acquired infection (diet and following medical procedures such as surgery, growth hormone injections, corneal transplants) i.e. infectious agent implicated.

  • Apparent heredity(sporadic CJD is about 1 /million per year)


Prospect
Prospect prions)

  • The mystery behind scrapie, kuru, and BSE has finally been unravelled.

  • Other dementias may have a similar background(Alzheimer's disease)


Diploma
Diploma prions)


Reference
Reference: prions)

  • http://www.nobel.se/

  • http://www.ucsf.edu/neurosc/faculty/neuro_prusiner.html

  • http://www-micro.msb.le.ac.uk/3035/prions.html


The End prions)


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