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Enostosis -like lesions. Katie Phillips. Hanz accession 147214. 12 yr old warmblood gelding Used for dressage 2 week history of lameness Presented for evaluation of a sore back. 3/5 Lame RF & LH. No change with flexion Could not be blocked . Hanz RF.

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Enostosis -like lesions

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Enostosis like lesions

Enostosis-like lesions

Katie Phillips

Hanz accession 147214

Hanzaccession 147214

  • 12 yr old warmblood gelding

  • Used for dressage

  • 2 week history of lameness

  • Presented for evaluation of a sore back.

  • 3/5 Lame RF & LH.

  • No change with flexion

  • Could not be blocked

Hanz rf

Hanz RF

Differentials: enostosis-like lesion, or less likely fracture, osteomyelitis, bone infarct, osteonecrosis. VRUS 2009

Hanz rh

Hanz RH



  • Scintigraphically as focal or multifocal areas of intense increased radioisotope uptake within the medullary cavity of long bones.

  • Radiographically as one or multiple round to irregular shaped opacities within the medullary cavity.

  • A mass of proliferating bone within a bone. –Stedman

  • A morbid bony growth developed within the cavity of a bone or on the internal surface of the bone cortex. -Dorland

Hanz radiographs

Hanz radiographs

Hanz radiographs1

Hanz radiographs

Well circumscribed intramedullary sclerosis with no apparent involvement of the cortex.

Enostosis like lesions in the literature

Enostosis-like lesions in the literature

  • Case reports and clusters of case reports, only.

  • All describe similar scintigraphy and radiographic findings.

  • Etiology is unknown

  • Often considered incidental

  • If no other cause of lameness is identified they are considered the cause.

  • O’Neil 2011 – report 15/21 cases where enostosis-like lesions were considered the cause of lameness.



  • Multiple breeds and disciplines described.

  • May be single or multiple lesions, often multiple limbs.

  • Frequently associated with dorsal endocortexdirectly across from nutrient foramen.

  • Lameness and lesions resolve with time.



Similarities to Canine Panosteitis

  • Radiopharmacutical uptake & medullary sclerosis

  • Nidus in vicinity of nutrient foramen

  • Radiographic changes don’t always correlate with lameness.

  • Similar temporal changes

  • Histologically the same

  • But… case reports are all horses in work (skeletally mature).

Human enostosis

  • AKA bone islands

  • Typically not scintigraphically active

  • Asymptomatic, static, solitary

  • Usually metaphyseal or epiphyseal

  • Bone Infarct

  • Case report in horse- showed colic like pain, then lameness.

  • Time line is different for scintigraphy changes and radiographic lag.

Enostosis like lesions


  • Case report 15yr WB

  • Only case in literature with histology!!

  • 4/5 lame LH localization was not possible.

  • Histo: No inflammatory cells, no thrombus, no evidence of bone necrosis. Similar to panosteitis of young dogs.

  • No histological involvement of endosteum.



  • Stieger-Vanegas, Kippenes-Skogmo, Nilsson. Imaging diagnosis- Enostosis-like lesion in the femur of a horse. 2009.VRUS.50(5) 509-512

  • Bassage, Ross. Enostosis-like lesions in the long bones of 10 horses:scintigraphic and radiographic features. 1998.Equine vet j. 30(1) 35-42

  • Ramzan.Equine enostosis-like lesions:12 cases 2002 EVE14(3) 143-148.

  • Jones & McDiarmid. Case report:Multiple enostosis-like lesions in a racing thoroughbred. 2005.eve. 17(2 92-95

  • O’Neil & Bladon.Retrospective study of scintigraphic and radiological findings in 21 cases of enostosis-like lesions in horses. 2011 veterinary record. 168:326

Mri travis 147695

MRI – Travis 147695

There are regions of intense medullary T2-hyperintensity in the third metatarsal bone at the level of the nutrient artery.  This appearance is consistent with enostosis but hematogenous osteomyelitis could also have this appearance.

Hanz follow up

Hanz – follow up

  • One dose IV Tildren

  • 2 months rest

  • Re-check: grade 1/5 lame RF, mildly positive to flexion LH.

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