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Osteoscoop – Issue N°56 – December 2008

European guidance for the diagnosis and management of osteoporosis in postmenopausal women – Therapeutic interventions. Osteoscoop – Issue N°56 – December 2008.

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Osteoscoop – Issue N°56 – December 2008

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  1. European guidance for the diagnosis and management of osteoporosis in postmenopausal women –Therapeutic interventions Osteoscoop – Issue N°56 – December 2008

  2. Antifracture efficacy of the most frequently used treatments for postmenopausal osteoporosis when given with calcium and vitamin D, as derived from randomised controlled trials Effect on vertebral fracture risk Effect on non-vertebral fracture risk Osteoporosis Established osteoporosis a Osteoporosis Established osteoporosis a Alendronate + + NA + (including hip) Risedronate + + NA + (including hip) Ibandronate NA + NA + b Zoledronic acid + + NA NA (+) c HRT + + + + Raloxifene + + NA NA Teriparatide/PTH NA + NA + Strontium ranelate + + + (including hip) + (including hip) NA: no evidence available +: effective drug a Women with a prior vertebral fracture b In subsets of patients only (post-hoc analysis) c Mixed group of patients with or without prevalent vertebral fractures

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