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Negri Body. An eosinophilic inclusion body found in the cytoplasm of certain nerve cells containing the rabies virus. Dementia with Lewy bodies (DLB). is one of the most common types of progressive dementia.

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Negri body
Negri Body

  • An eosinophilic inclusion body found in the cytoplasm of certain nerve cells containing the rabies virus.


Dementia with lewy bodies dlb
Dementia with Lewy bodies (DLB)

  • is one of the most common types of progressive dementia.

  • alpha-synuclein accumulation is also linked to Parkinson's disease, multiple system atrophy, and several other disorders, which are referred to as the "synucleinopathies.“

  • It is characterized anatomically by the presence of Lewy bodies-- clumps of alpha-synuclein and ubiquitin protein in neurons, detectable in post-mortem brain biopsies.

  • in people with no known family history of the disease


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