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Coordinating Center Plans for Dissemination and Extensions James Gordon, EdD, PT, FAPTA

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PTClinResNet. Coordinating Center Plans for Dissemination and Extensions James Gordon, EdD, PT, FAPTA Co-Principal Investigator. Annual Investigators Meeting: PT2005, Boston, MA, June 8, 2005. Purpose…. What have we accomplished? What did it cost? What is left to do?

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PTClinResNet

Coordinating Center

Plans for Dissemination and Extensions

James Gordon, EdD, PT, FAPTA

Co-Principal Investigator

Annual Investigators Meeting: PT2005, Boston, MA, June 8, 2005

purpose
Purpose…
  • What have we accomplished?
  • What did it cost?
  • What is left to do?
  • Where do we go from here?
what have we accomplished
What have we accomplished?
  • Established a true clinical research network
    • National scope
    • Regional elaboration
  • Demonstrated its feasibility and usefulness
    • More so within PT community
what have we accomplished1
What have we accomplished?
  • Met (or stayed close to) our recruitment goals!!!
    • This is a significant accomplishment
      • It is estimated that 80% of all clinical trials fail to meet recruitment goals (Marks et al, Statist. Med. 2001; 20:2683–2696)
what have we accomplished2
What have we accomplished?
  • Developed extensive manual of procedures
    • Standardization of assessments and treatment protocols
  • Established Data Management Center
  • Built institutional infrastructures
  • Gained valuable experience
what have we accomplished3
What have we accomplished?
  • Begun to disseminate methods
    • Conferences and other presentations
      • CSM 2004, CPTA, CSM 2004
      • RehabNetWest Clinical Trials Symp. 2004
      • AACPDM 2005
    • Ready to disseminate MOP through website
  • Begun to analyze data
    • Preliminary results look promising
what have we accomplished4
What have we accomplished?
  • Begun to successfully extend the network to other funded studies
    • NIDDR Field-Initiated Grant Proposal (Brown) – pending decision
    • SBIR with Afferent Corp. (Brown)
    • PERKS (Gordon & Fisher) – Parkinson’s Exercise Research Kinetics Study ($400K over 2 years)
what have we accomplished5
What have we accomplished?
  • Begun to successfully extend the network to other funded studies
    • UCP (Fowler) $99K over 3 years
    • Steimetz Foundation (Fowler) $36K for PEDALS
    • Donations totaling over $35K
what have we accomplished6
What have we accomplished?
  • Begun to successfully extend the network to other funded studies
    • LEAPS (Duncan, Sullivan, Behrman, Azen) Locomotor Experience Applied Post-Stroke ($13.2 million over 5 years) pending
    • ICARE (Winstein, Wolf, Dromerick) Interdisciplinary Comprehensive Arm Rehabilitation Evaluation ($10 million over $5 years) pending
what did it cost2
What did it cost?
  • Institutional support may not be so easy to get in the future…
    • Conditions were right for PTClinResNet
  • NIH moving to funding per recruited subject in large clinical trials
    • Worth examining as a future strategy
what is left to do
What is left to do?
  • Finish studies!
    • Complete recruitment
    • Data Analysis
    • Write papers
  • Marketing the PT CRN
    • Within PT
    • Outside “consumers”
where do we go from here
Where do we go from here?
  • The future of clinical research: interdisciplinary studies
    • See NIH roadmap
    • Stress on interdisciplinary teams & “re-engineering clinical research)
  • Example
    • ISNSR (USC/UT Exploratory Center for the Interdisciplinary Study of Neuroplasticity and Stroke Rehabilitation )
the challenge
The Challenge!
  • How to make sure that physical therapy is part of the evolving (interdisciplinary) landscape of clinical research
  • At the same time, continue to get support from practicing PT’s
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