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PTClinResNet. Coordinating Center Plans for Dissemination and Extensions James Gordon, EdD, PT, FAPTA Co-Principal Investigator. Annual Investigators Meeting: PT2005, Boston, MA, June 8, 2005. Purpose…. What have we accomplished? What did it cost? What is left to do?

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PTClinResNet

Coordinating Center

Plans for Dissemination and Extensions

James Gordon, EdD, PT, FAPTA

Co-Principal Investigator

Annual Investigators Meeting: PT2005, Boston, MA, June 8, 2005


Purpose
Purpose…

  • What have we accomplished?

  • What did it cost?

  • What is left to do?

  • Where do we go from here?


What have we accomplished
What have we accomplished?

  • Established a true clinical research network

    • National scope

    • Regional elaboration

  • Demonstrated its feasibility and usefulness

    • More so within PT community


What have we accomplished1
What have we accomplished?

  • Met (or stayed close to) our recruitment goals!!!

    • This is a significant accomplishment

      • It is estimated that 80% of all clinical trials fail to meet recruitment goals (Marks et al, Statist. Med. 2001; 20:2683–2696)


What have we accomplished2
What have we accomplished?

  • Developed extensive manual of procedures

    • Standardization of assessments and treatment protocols

  • Established Data Management Center

  • Built institutional infrastructures

  • Gained valuable experience


What have we accomplished3
What have we accomplished?

  • Begun to disseminate methods

    • Conferences and other presentations

      • CSM 2004, CPTA, CSM 2004

      • RehabNetWest Clinical Trials Symp. 2004

      • AACPDM 2005

    • Ready to disseminate MOP through website

  • Begun to analyze data

    • Preliminary results look promising


What have we accomplished4
What have we accomplished?

  • Begun to successfully extend the network to other funded studies

    • NIDDR Field-Initiated Grant Proposal (Brown) – pending decision

    • SBIR with Afferent Corp. (Brown)

    • PERKS (Gordon & Fisher) – Parkinson’s Exercise Research Kinetics Study ($400K over 2 years)


What have we accomplished5
What have we accomplished?

  • Begun to successfully extend the network to other funded studies

    • UCP (Fowler) $99K over 3 years

    • Steimetz Foundation (Fowler) $36K for PEDALS

    • Donations totaling over $35K


What have we accomplished6
What have we accomplished?

  • Begun to successfully extend the network to other funded studies

    • LEAPS (Duncan, Sullivan, Behrman, Azen) Locomotor Experience Applied Post-Stroke ($13.2 million over 5 years) pending

    • ICARE (Winstein, Wolf, Dromerick) Interdisciplinary Comprehensive Arm Rehabilitation Evaluation ($10 million over $5 years) pending




What did it cost2
What did it cost?

  • Institutional support may not be so easy to get in the future…

    • Conditions were right for PTClinResNet

  • NIH moving to funding per recruited subject in large clinical trials

    • Worth examining as a future strategy


What is left to do
What is left to do?

  • Finish studies!

    • Complete recruitment

    • Data Analysis

    • Write papers

  • Marketing the PT CRN

    • Within PT

    • Outside “consumers”


Where do we go from here
Where do we go from here?

  • The future of clinical research: interdisciplinary studies

    • See NIH roadmap

    • Stress on interdisciplinary teams & “re-engineering clinical research)

  • Example

    • ISNSR (USC/UT Exploratory Center for the Interdisciplinary Study of Neuroplasticity and Stroke Rehabilitation )



The challenge
The Challenge!

  • How to make sure that physical therapy is part of the evolving (interdisciplinary) landscape of clinical research

  • At the same time, continue to get support from practicing PT’s



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