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American Indian / Alaska Native (AIAN) Cancer 101

American Indian / Alaska Native (AIAN) Cancer 101. Module 9: Chronic Conditions and Cancer. Acknowledgements. Thank you Katherine J. Briant, MPH, CHES Community Health Educator Center for Community Health Promotion Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N., M3-B232

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American Indian / Alaska Native (AIAN) Cancer 101

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  1. American Indian / Alaska Native (AIAN) Cancer 101 Module 9: Chronic Conditions and Cancer

  2. Acknowledgements Thank you Katherine J. Briant, MPH, CHES Community Health Educator Center for Community Health Promotion Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N., M3-B232 P.O. Box 19024 Seattle, WA 98109 Tel:  206-667-1137 Fax:  206-667-5977 for drafting original slides for Module 9: Chronic Conditions and Cancer Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  3. Please turn off your cell phones or switch them to “vibrate” mode

  4. Module 9 Objectives for Chronic Conditions and Cancer. By the end of this session the participant will be able to: • Distinguish between a health condition that is acute versus one that is chronic. • Identify at least 3 common chronic conditions in AIAN communities. • Describe at least 5 risk factors for chronic conditions.

  5. Module 9 Objectives for Chronic Conditions and Cancer. By the end of this session the participant will be able to: • Describe how co-morbidities impact cancer and quality of life. • Explain the differences between acute, chronic and late effects of cancer and cancer treatment • Identify at least 5 strategies for addressing chronic side effects of cancer/cancer treatment

  6. Historical Footprint • Chronic diseases were rare among our ancestors • Where we are now with chronic diseases evolved from living on Reservations for 7 generations Curtis photograph of Kerri Lopez’s grandmother, Ada Richards (Tolowa Nation) Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  7. I want my grandchildren to live long, healthy lives like our ancestors. Today we forget how to act in ways that honor those who came before us. Our ancestors didn’t have these diseases. Anonymous AI, 2011 QUESTION: Why is Understanding Chronic Conditions Important to AIANs? • Leading causes of death among adult AIANs • Leading causes of conditions that interfere with our daily quality of life Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  8. Objective 1: Distinguish between a health condition that is acute versus one that is chronic.

  9. Definitions • Acute (uh-KYOOT) condition:   • A condition or disease that begins and worsens quickly. • If managed well will resolve (or improve and become chronic). • What would be an example of an acute illness? Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  10. Common Acute Conditions • Cold or flu • Infection • Trauma (car accident, broken leg) • Allergic reactions Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  11. Definitions • Chronic (KRAH-nik) condition: • A condition or disease that persists or progresses over a long period of time. • May have previously been acute • Can be managed, but usually does not go away completely • What would be an example of a chronic condition? Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  12. Common Chronic Conditions • Heart Disease • Cancer • Diabetes • High blood pressure (hypertension) Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  13. My doctor wouldn’t listen to me or to my husband. Finally they learned that I had a heart condition, probably from my chemo. Characteristics of Chronic Conditions • Lasts one year or longer • Requires ongoing medical care • Limits daily activities • Often interferes with one’s quality of life Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  14. Objective 2 Identify at least 3 common chronic conditions in the AIAN communities.

  15. Common Chronic Conditions • The most common, costly, and preventable chronic conditions in the U.S. are: • Heart disease • Cancer • Diabetes • Arthritis • Obesity • This is true for AIANs too Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  16. Other Chronic Conditions • Stroke • Substance abuse and addiction disorders • Mental illness • Dementia • Cognitive impairment disorders • Developmental disabilities • Heart disease, cancer and stroke account for ½ of all deaths each year. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  17. Cancer Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  18. Cost of Chronic Conditions or all Americans • Annual healthcare costs = $2.5 trillion • Heart Disease = $108.9 Billion • Stroke = $53.9 Billion • Hypertensive = $93.5 Billion (CDC 2010) • Cancer = $263.8 Billion in medical cost and lost productivity (CDC 2010) • Diabetes = $132 Billion (IHS 2002) • Obesity: $450 Billion Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  19. Heart (Cardiovascular) Disease (CVD) • AIANs have the highest percentage (36%) of deaths from premature heart disease. • This is nearly 2½ times that of whites. • AIANs have more risk factors for CVD than do Non-Hispanic Whites • Obese • High blood pressure (21% to 41% AIs) • Commercial tobacco use (15 to 70% AIs) Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  20. Diabetes • Type 2 diabetes is caused by the body’s resistance to the action of insulin and by impaired insulin secretion. • Higher blood levels of HbA1c suggests an increased risk for the development of diabetes. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  21. Diabetes (cont) • Most AIANs with diabetes have type 2, which usually develops in adults but within AIAN communities it is no longer uncommon for diabetes to develop in children and adolescents. • A small number (2-4%) of AIANs have type 1 diabetes. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  22. Diabetes (cont) Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI) • The “TRIPLE TRIPLE”of diabetes in Native America • ~3x risk of heart disease and stroke • 3.5x risk of kidney failure • 3x rate of death

  23. Diabetes (cont) 7% weight loss from 150 min of activity per week and healthy meals can reduce the risk of diabetes by > 50% Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI) Diabetes can be PREVENTED Disease and early death is not inevitable. It is never too late to change and improve health. Family & community efforts are the key

  24. Arthritis • Arthritis is the most common cause of disability. • 25.2% of AIs have arthritis; ~ 40% have activity limitations and ~38% have work limitations • The prevalence high in Alaska (26.1%) and low in the Southwest (16.5%) as compared with the US pop. (21.5%). http://www.cdc.gov/arthritis/data_statistics/race.htm Arthritis Rheum. 2008 Aug 15;59(8):1128-36. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  25. Arthritis • Having arthritis increases risk of dying from cancer, but not being diagnosed with cancer John Wiley & Sons, Inc. (2007, February 27). Link Between Rheumatoid Arthritis And Cancer. ScienceDaily. Retrieved January 10, 2012, from http://www.sciencedaily.com­ /releases/2007/02/070227105344.htm Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  26. Obesity • Over the past 3 decades, being overweight or obese has become a major health concern. • Obesity is a risk factor for many other chronic conditions • the number of adults and children who meet the definition for obesity has more than doubled. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  27. Obesity is the Root of a Deadly Tree Hyperuricemia Dysthrombosis (PAI-1) Inflammation (CRP) Dyshormonal (Polycystic Ovary Syndrome) Pre-diabetes Type 2 diabetes Endothelial Dysfunction (Nitric Oxide) Hyperlipidemia (high TG low HDL) Dermatologic (Acanthosis Nigricans) Insulin Resistance Hypertension Modify slide for 5 most common chronic diseases Free Fatty Acids Lipolysis – fatty breakdown Obesity - Waist circumference Calories In >>>> Calorie Excess >>Calories Out Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI) Sedentary lifestyle + genetics (?)

  28. Cancer • Now considered a chronic disease • Most common types among AIANs are: • Lymphoma • Lung & Bronchus • Colon & Rectum • Corpus & Uterus • Kidney & Renal • Breast • Ovarian • Pancreas • Cervix • Thyroid Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  29. Objective 3 Describe at least 5 risk factors for chronic conditions.

  30. Examples of “Risk Factors” • Foods and drinks we consume • Lack of physical activity • Exposure to environmental contaminants • Spiritual distress • Social distress (dysfunctional families, neighbors or work settings) Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  31. Additional Risk Factors • Not actually risk factors, but increase the likelihood that a problem or condition is not managed well and may become acute or chronic • Healthcare access and screening services • Affordable quality health care Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  32. What “makes” something a bigger “risk” for chronic conditions? Frequency how often does the “risk” or behavior happen? (e.g., smoke >2 packs of cigarettes a day) Duration how long does the “risk” or behavior last? (e.g., smoked since 14 years old) Intensity how strong is the dosage of the “risk” or behavior? (e.g., smoke Marlboro -- high nicotine cigarettes) Cancer 100 “Overview of Cancer” (Burhansstipanov) Native Navigators and the Cancer Continuum (NNACC) [NCMHD R24MD002811] Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI) 32

  33. Behavioral Risk Factors • Alcohol (~ >7 for women or >14 for men drinks a week) is a risk factor for: • Diabetes • Obesity • Liver and kidney disease • Cancers, such as • Breast • Colon • Lung • Prostate Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  34. Behavioral Risk Factors • Heart • Diabetes • Arthritis • Habitual tobacco use (or “secondhand smoke”) is a risk factor for: Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  35. Smoking Disparities by State Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  36. Behavioral Risk Factors • Habitual tobacco use (continued) • Cancers, such as: • Cervix • Colorectal • Esophageal • Lung • Stomach • Pancreas • Prostate • NOTE: “Ceremonial tobacco use” typically is not a risk because there is short • frequency • duration • intensity (dosage) Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  37. Behavioral Risk Factors Non-Traditional use tobacco smokers are 30-40% more likely to die from colon cancer Smoking rates in most IHS regions > 40% Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  38. Behavioral Risk Factors • Obesity is a risk factor for: • Heart disease (and other CVD, like stroke) • Diabetes • Arthritis • Cancers, such as • Breast • Colorectal • Gallbladder • Prostate • “Obesity” = “Body Mass Index” (BMI) more than 30 • Usually at least 25 pounds over recommended weight Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  39. Behavioral Risk Factors • Unhealthy (high fat, high sugar, white starches, low fiber, low intake of fruits and vegetables) diet is a risk factor for: • Heart disease (and other CVD, like stroke) • Diabetes • Obesity • Cancers, such as: • Breast • Colorectal • Gallbladder • Prostate Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  40. Behavioral Risk Factors • Sedentary (not physically active) behaviors are a risk factor for: • Heart disease (and other CVDs) • Diabetes • Obesity • Arthritis • Depression / Suicide • Substance abuse Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  41. Behavioral Risk Factors • Sedentary lifestyle (continued) • Cancers, such as • Breast • Colorectal • Gallbladder • Prostate Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  42. Behavioral Risk Factors • More than three sexual partners throughout your lifetime (not all at the same time …. ahem!) • Increased risk of HPV • Increased risk of cervical cancer Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  43. Environmental Risk Factors • Exposure to contaminants through home, work, fishing, hunting or hobbies such as: • Ionizing radiation • Pesticides • Medical drugs • Solvents • Fibers, Fine Particles, Dust • Tobacco • Alcohol • Ultraviolet radiation (sunlight) • Viruses, Bacteria • Dioxins *Cancer and the Environment (2003). NIH Publication No. 03-2039. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  44. Environmental Risk Factors • Exposure to: • Polycyclic aromatic hydrocarbons (PAH) • Metals (mercury) • Diesel exhaust particles • Toxins from fungi • Vinyl Chloride • Benzene • PCBs *Cancer and the Environment (2003). NIH Publication No. 03-2039. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  45. Environmental Risk Factors • Exposure to environmental contaminants is a risk factor for: • Heart • Diabetes • Arthritis • Lung diseases (emphysema; COPD) *Cancer and the Environment (2003). NIH Publication No. 03-2039. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  46. Environmental Risk Factors • Exposure to environmental contaminants is a risk factor for: • Cancers such as: • Lung • Cervix • Lymphoma • Breast • Thyroid • Head and neck • Skin *Cancer and the Environment (2003). NIH Publication No. 03-2039. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  47. Social Risk Factors • Healthcare access and screening services, such as: • Lack of Transportation (distance) • Insufficient / Non-existent local screening services • Lack of child / elder care • Lack of 1st language (Native tongues spoken) • Time off work to attend to health needs Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  48. Social Risk Factors • Affordable quality health care, such as: • Timely access or CHS referral to care / treatment • (average 6 months from biopsy to initiation of breast cancer treatment of AIAN women who must rely on IHS referrals for care) • Lack of appointments in tribal / urban health clinics for several months Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  49. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

  50. Social Risk Factors • Affordable quality health care (cont.) • 34% of AIANs have private health insurance • Surveys erroneously collapse AIAN’s responses of “yes, I have IHS” as health insurance • Beginning in 1998, the US Census Bureau ceased counting IHS eligibility as “health insurance coverage. Mayo Clinic’s “Spirit of EAGLES Community Network Programs 2” [P.I. Kaur; U54CA153605] ; Northwest Portland Area Indian Health Board; Native American Cancer Initiatives, Incorporated (NACI)

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