TUBERCULOSIS Diagnosis & treatment. Dr. Fazli Wahab FCPS(Med), FCPS( Pulmonology ) Assisstant Prof Peshawar Medical College. Diagnostic Tools. Microscopy AFB smear Histology AFB Culture Radiology Tuberculin skin test Serological Tests. AFB smear. Rapid and inexpensive. Granuloma.
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Assisstant Prof Peshawar Medical College
Rapid and inexpensive
The "classic" picture is that of upper-lobe disease with infiltrates and cavities,
Test TB infection in adults and children
1ST LINE DRUGS:
Standard short course regimens 6-8 months.
An initial, intensive or bactericidal, phase and
A continuation, or sterilizing, phase.
DOTS(directly observed treatment, short-course), the WHO-recommended TB control strategy.
Initial Intensive Phase
HRZE : 2 Months
HR: 4months OR HE: 6 Months
INITIAL INTENSIVE PHASE (3months)HRZES: 2MONTHS Then HRZE:1 Month
HRE: 5 Months
The ultimate result is the multidrug-resistant TB (MDR-TB) or extensively-drug resistant TB (XDR-TB)
In MDR-TB the Mycobacterium Tuberculosis is resistant to Rifampacin and INH with or without resistance to other 1st ATT.
Treatment is difficult and expensive.