Cardiac Pathophysiology. Pericarditis. Often local manifestation of another disease May present as: Acute pericarditis Pericardial effusion Constrictive pericarditis. Acute Pericarditis. Acute inflammation of the pericardium
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Accumulation of fluid in the pericardial cavity
May be transudate
May be exudate
May be blood
Not clinically significant other than to indicate underlying disorder, unless:
Pressure becomes sufficient to cause cardiac compression – cardiac tamponade
↓ C.O.; ↑ thrombi formation ; ↓ contractility, and mitral valve incompetence, arrhythmias Tx: relieve symptoms of heart failure, decrease workload, and anticoagulants; transplants
C.O. is normal,↑ inflow resistance, and mitral valve incompetence, arrhythmais and sudden death.
Reduced diastolic compliance of the ventricle. C.O. is normal or↓;↑ formation of thrombi, dilation of left atrium, and mitral valve incompetence.
(or insufficiency or incompetence)
Causes increased work of LV
→ LV dilation & hypertrophy as compensation
→ prolonged contractions as compensation
Finally heart overwhelmed