Cardiac Pathophysiology. Pericarditis. Often local manifestation of another disease May present as: Acute pericarditis Pericardial effusion Constrictive pericarditis. Acute Pericarditis. Acute inflammation of the pericardium
Accumulation of fluid in the pericardial cavity
May be transudate
May be exudate
May be blood
Not clinically significant other than to indicate underlying disorder, unless:
Pressure becomes sufficient to cause cardiac compression – cardiac tamponade
↓ C.O.; ↑ thrombi formation ; ↓ contractility, and mitral valve incompetence, arrhythmias Tx: relieve symptoms of heart failure, decrease workload, and anticoagulants; transplants
C.O. is normal,↑ inflow resistance, and mitral valve incompetence, arrhythmais and sudden death.
Reduced diastolic compliance of the ventricle. C.O. is normal or↓;↑ formation of thrombi, dilation of left atrium, and mitral valve incompetence.
(or insufficiency or incompetence)
Causes increased work of LV
→ LV dilation & hypertrophy as compensation
→ prolonged contractions as compensation
Finally heart overwhelmed