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A. PM1

a-CD3. A. PM1. C. RANTES. MIP-1b. Ionomycin. a-CD3. B. PBMCs. RANTES. MIP-1b. Functional CXCR4 is present on all cell lines; CCR5 is either absent, or defective in signal transduction. X4 gp20 enhances Type 1 & 2 EBV transformation; R5 may suppress Type 1 transformation.

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A. PM1

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  1. a-CD3 A. PM1 C. RANTES MIP-1b Ionomycin a-CD3 B. PBMCs RANTES MIP-1b Functional CXCR4 is present on all cell lines; CCR5 is either absent, or defective in signal transduction.

  2. X4 gp20 enhances Type 1 & 2 EBV transformation; R5 may suppress Type 1 transformation Low efficiency AG876 High efficiency B95.8 Low efficiency AG876 c

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