1 / 12

Tuberculosis: the Main Opportunistic Infection in Ukraine

Tuberculosis: the Main Opportunistic Infection in Ukraine. Tetyana Loginova Kiev City Narcological Hospital " Sociotherapy ".

hunter
Download Presentation

Tuberculosis: the Main Opportunistic Infection in Ukraine

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Tuberculosis: the Main Opportunistic Infection in Ukraine TetyanaLoginovaKiev City Narcological Hospital "Sociotherapy"

  2. Tuberculosis (TB) epidemiy in Ukraine was officially pronounced by Ministry of Health in 1995. TB reached its peak in 2005 when official data increased three times compared with pre-epidemic period (approximately 100 cases for 100 000 people). • During last 15 years, Governmental measures towards TB prevention included anti-TB medications purchases, as well as consequent realization of two “Global Governmental programs of countermeasures towards TB” that allowed to slow further spreading of epidemy in Ukraine, and lowered TB number to approximately 25 % compared with its worst situation in 2005. Based on WHO, there are certain advances in Ukraine, which undoubtedly helped to slow TB epidemy. In the official report on Global TB struggle in 2012, Ukraine fortunately did not make it to the list of 22 countries with largest TB numbers.

  3. To date, there are 102 cases of TB-infection registration and four lethal cases on a daily basis. This situation is caused by social-democratic and medical conditions, such as lowering of the population level and the presence of the sick imprisoned people (over 10 000), lack of financial support of the institutions, lack of qualified medical staff, and spreading of the chimioresistance of TB. • In 2012, TB infection had a tendency of growth compared with 2011 (with about 1.3% increase, that is, 67.2 to 68.1 on 100 000 population). The decline of the epidemic situation with TB is also caused by HIV/AIDS factor in Ukraine. Over 30% of HIV-infected patients are infected with TB, and over 40% of them die because of HIV/AIDS. HIV infection is a powerful factor that allows development of the TB active form in carriers of latent infection, as well as increase of possibility of TB relapse. Based on Governmental Statistic Service, mortality indicator in 2012 was 15.1 to 100 000 population.

  4. N1. Case rate for active TB among Ukraine population in 2012 (for 100 000)

  5. N2. Case rate for active TB among Ukraine population for cities and villages residents

  6. N3.Number of registered cases of the established multiresistant TB Thank to adjusted diagnostics by using modern methods (GeneXpert &Bactech), detectability of the multiresistant TB increased.

  7. N4.Efficacy of treatment by using positive smear at primer TB diagnostic, registered in 2011 (in accord with cohort analysis)

  8. Low rate of the treatment efficacy is caused by high rates of: • Unsuccessful treatment: 19.6% (goal: 3-5%), which indicates insufficient monitoring of the treatment, spreading of the TB/HIV co-infections in high level of multiresistant TB (9.8% cases – failure with transfer to 4th category). • Lethal cases: 14.1% (goal <5%), of which 7.7% are TB/HIV co-infected, that do not fully provide ART, which caused mortality. • Interrupted treatment of 7.5% (goal 3%), which indicates low adherence of the patients and unsatisfactory social support of TB patients during the therapy (nutritional, social and medical support, etc.) • Transferred 3.5%, which means disadvantages of the system of TB-cases registration.

  9. TB 10000 5000 TBex BI 2000 CD-4<200 HIV Slim CanBr CanES HS PCP TG CMV SK Opportunistic InfectionsTotal on 01.01.2013:24090

  10. 7000 TB 5000 AIDS 3000 TB+AIDS 2010 2011 2012 Mortality rate

  11. 7000 TB 5000 TB+AIDS AIDS 3000 2008 2010 2012 2006 TB+AIDS Morbidity (black)TB Mortality (blue)AIDS Mortality (red)

  12. Conclusions For effective TB detection, diagnostics, and treatment, following points can be summarized: • To reduce the consequences of TB epidemics, anti-TB institutions have to be integrated into the AIDS centers, and their funding should be considerably increased. • Everybody from marginalized group of population has to be examined by X-ray minimum once a year. • To implement new mobile X-ray equipment for examination of large population groups in villages and marginalized people (drug addicts, alcoholics, homeless). • To extend implementation of modern laboratory methods (GeneXpert and Bactech) in practice for quick diagnostic tuberculosis, to isolate TB patient and to start treatment on time. • To organize work places for medical staff according to TB control rules for TB prevention among them.

More Related