1 / 12

Ad-hoc Disease Transmission Advisory Committee

Guidance on Explaining Risk Related to Use of Increased Risk Donor Organs When Considering Organ Offers. Ad-hoc Disease Transmission Advisory Committee. What problem will the proposal solve?. What are the proposed solutions?. Supporting Evidence. Based on OPTN data as of May 27, 2016.

hugley
Download Presentation

Ad-hoc Disease Transmission Advisory Committee

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Guidance on Explaining Risk Related to Use of Increased Risk Donor Organs When Considering Organ Offers Ad-hoc Disease Transmission Advisory Committee

  2. What problem will the proposal solve?

  3. What are the proposed solutions?

  4. Supporting Evidence Based on OPTN data as of May 27, 2016

  5. Supporting Evidence Estimated risk of window period infection (per 10,000 donors) Kucirka, LM, Bowring,,MG, Massie, AB, Luo, X, Nicholas, LH, Segev, DL, "Landscape of Deceased Donors Labeled Increased Risk for Disease Transmission Under New Guidelines. "American Journal of Transplantation 15, no. 12 (2015): 3215-3223 Kucirka, LM, Sarathy, H, Govindan, P, Wolf, JH, Ellison, TA, Hart, LJ, et al, "Risk of Window Period Hepatitis-C Infection in High Infectious Risk Donors: Systematic Review and Meta-analysis," American Journal of Transplantation 11, no. 6 (2011):1188-1200

  6. Supporting Evidence Estimated risk of window period infection (per 10,000 donors) Kucirka, LM, Bowring,,MG, Massie, AB, Luo, X, Nicholas, LH, Segev, DL, "Landscape of Deceased Donors Labeled Increased Risk for Disease Transmission Under New Guidelines. "American Journal of Transplantation 15, no. 12 (2015): 3215-3223 Kucirka, LM, Sarathy, H, Govindan, P, Wolf, JH, Ellison, TA, Hart, LJ, et al, "Risk of Window Period Hepatitis-C Infection in High Infectious Risk Donors: Systematic Review and Meta-analysis," American Journal of Transplantation 11, no. 6 (2011):1188-1200

  7. Supporting Evidence Estimated risk of window period infection (per 10,000 donors) Kucirka, LM, Bowring,,MG, Massie, AB, Luo, X, Nicholas, LH, Segev, DL, "Landscape of Deceased Donors Labeled Increased Risk for Disease Transmission Under New Guidelines. "American Journal of Transplantation 15, no. 12 (2015): 3215-3223 Kucirka, LM, Sarathy, H, Govindan, P, Wolf, JH, Ellison, TA, Hart, LJ, et al, "Risk of Window Period Hepatitis-C Infection in High Infectious Risk Donors: Systematic Review and Meta-analysis," American Journal of Transplantation 11, no. 6 (2011):1188-1200

  8. Supporting Evidence Modified from: Annambhotla PD, Gurbaxani BM, Kuehnert MJ, Basavaraju SV, “A model to estimate the probability of human immunodeficiency virus and hepatitis C infection despite negative nucleic acid testing among increased-risk organ donors”. Transplant Infectious Disease, 2017 Feb 8. doi: 10.1111/tid.12676

  9. Supporting Evidence Risk of getting HIV or HCV from a “PHS increased risk” organ versus risk of dying from a traffic accident Kucirka, LM, et al, Risk of Window Period HIV Infection in High Infectious Risk Donors: Systematic Review and Meta-Analysis”, American Journal of Transplantation 11, no 6 (2011): 1176-1187. Images created by Iconarray.com. Risk Science Center and Center for Bioethics and Social Sciences in Medicine, University of Michigan. Accessed November 22, 2016 Kucirka, LM, “Risk of Window Period Hepatitis-C Infection in High Infectious Risk Donors: Systematic Review and Meta-Analysis”, American Journal of Transplantation 11, no 6 (2011): 1188-1200. Images created by Iconarray.com. Risk Science Center and Center for Bioethics and Social Sciences in Medicine, University of Michigan. Accessed November 22, 2016

  10. How will members implement this proposal?

  11. How will the OPTN implement this proposal?

  12. Questions? Cameron R. Wolfe, M.D. Committee Chair cameron.wolfe@duke.edu Christopher L. Wholley, M.S.A. Committee Liaison christopher.wholley@unos.org

More Related