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Artificial Skin. By: Raymond Litteaur. History of Burns. Before artificial skin was developed, burns covering 50% of the body were considered to be fatal. In 2000, artificial skin cut death rates in people with over 70% burns from 100% to 40%.

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Artificial skin
Artificial Skin

By: Raymond Litteaur


History of burns
History of Burns

  • Before artificial skin was developed, burns covering 50% of the body were considered to be fatal.

  • In 2000, artificial skin cut death rates in people with over 70% burns from 100% to 40%.

  • Skin is the body’s largest organs and protects us from physical damage, disease, and controls our body’s temperature.


How artificial skin is made
How Artificial Skin is Made

  • Skin is usually donated by other donors.

  • Fibroblasts are removed from the donated skin and are frozen until they are needed.

  • The fibroblasts are placed on a polymeric mesh scaffolding, gather oxygen, and grow new cells.

  • The cells are then transferred to a culture system.


Artificial skin cont
Artificial Skin cont.

  • After 4 weeks the polymer mesh dissolves and leaves behind a new layer of dermal skin.

  • When the growth cycle is completed, they add more nutrients.

  • Keratinocytes are added to the collagen and are exposed to air to form epidermal layers.

  • The skin is now completed and is stored in sterile contains until ready to use.


How artificial skin is used
How Artificial Skin is Used

  • Artificial skin is already being used for burn victims and soon will be available for other skin disorders.

  • The skin is not used for a permanent replacement, but to temporary cover the skin until your skin can grow back naturally.


The future
The Future

  • Because skin is an organ, there are many similarities between skin and other organs.

  • There is hope to regenerate joints, ears, noses, livers, kidneys, and hearts.


References
References

  • GAO Report. 31 May 2005. GAO-05-759T. “Advanced Technology Program: Inherent Factors in Selection Process Are Likely to Limit Identification of Similar Research”<http://www.gao.gov/htext/d05759t.html>

  • McNulty, Mary F. “Artificial Skin”. <http://www.gale-edit.com/products/volumes/skin.htm>

  • Smith, Carol. 23 Feb. 2001. “Artificial skin offers genuine hope” <http://seattlepi.nwsource.com/local/burn231.shtml>

  • T.J. Samson Community Hospital. 1 Jan 2005. “Artificial Skin” <http://tjsamson.client.web-health.com/web-health/topics/GeneralHealth/generalhealthsub/generalhealth/skin&hair&nails/AGING&COSMETIC/skin_artificial.html>

  • Pictures:

  • http://www.devicelink.com/mddi/archive/98/05/018.html

  • http://www.biomed.metu.edu.tr/courses/term_papers/artificial%20skin_cinar.htm


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