1 / 2

star

Volle_FigS1. SHP L2/L2. SHP L2/L2. SHP L2/L2. SHP L2/L2. SHP L2/L2. SHP L-/L-. SHP L-/L-. SHP L-/L-. SHP L-/L-. SHP L-/L-. a. b. c. 6. 6. 80. 5. *. 4. 60. 4. Relative mRNA expression. Fold induction. Fold induction. 3. 40. 2. *. 2. 20. 1. 0. 0. 0. 28. 30. 28.

howe
Download Presentation

star

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Volle_FigS1 SHPL2/L2 SHPL2/L2 SHPL2/L2 SHPL2/L2 SHPL2/L2 SHPL-/L- SHPL-/L- SHPL-/L- SHPL-/L- SHPL-/L- a b c 6 6 80 5 * 4 60 4 Relative mRNA expression Fold induction Fold induction 3 40 2 * 2 20 1 0 0 0 28 30 28 30 veh hCG veh hCG veh hCG lrh-1 sf-1 Testosterone star cyp11a1 d e f Number of KI67 positive cells for 100 tubes Number of apoptotic cells for 100 tubes 100 35 pem claudin 11 3 * 30 80 4 * 25 2 60 3 Relative mRNA expression 20 Relative mRNA expression 15 40 2 1 10 20 1 5 0 0 0 0 25d 28d 25d 28d 11 15 20 28 30 11 15 20 28 30 days days days days

  2. Volle_FigS2 SHPL2/L2 SHPL-/L- a SacI HindIII SacI HindIII SacI Genomic locus 1 2 1 2 neo pBS pBS Targeting vector SacI SacI HindIII SacI L3 1 2 neo L2 1 2 HindIII HindIII SacI Deleted allele (L-) c b L2/L2 L2/L- L-/L- 2 Relative mRNA expression 1 500pb 400pb 300pb 0 Liver Testis

More Related