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Improving CABG Surgery

Improving CABG Surgery. Amir Durrani Ben Hoagland Santosh Tumkur Lucas Burton Advisor: Thomas P. Ryan, Ph.D. Project Goals. Improve harvested vessel attachment Design device to aid in grafting Reduce suturing difficulty Improve local stabilization. Overview of Off-Pump CABG.

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Improving CABG Surgery

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  1. Improving CABG Surgery Amir Durrani Ben Hoagland Santosh Tumkur Lucas Burton Advisor: Thomas P. Ryan, Ph.D.

  2. Project Goals • Improve harvested vessel attachment • Design device to aid in grafting • Reduce suturing difficulty • Improve local stabilization

  3. Overview of Off-Pump CABG • Coronary Artery Bypass Graft • Procedure to introduce increased blood flow to occluded coronary arteries • Harvested vessels grafted to coronary arteries

  4. Market Potential • 150,000 Off-pump CABG surgeries performed worldwide each year • Charge for a CABG procedure ranges from $37,000 and $72,000 per case • $26 Billion spent per year on CABG surgeries • Use of beating heart techniques has grown more than 40% each year since 1997

  5. Problems • Stabilization is required to perform CABG on a beating heart • Effective vessel-artery contact is imperative • Complex suturing techniques required • Current stabilizers don’t provide adequate local stabilization of graft site • Heart positioning problems • Heart hemodynamics

  6. Possible Solution 1 Intra-vascular component Absorbable Biocompatible Beveled attachment point Y-joint grafting device Shunt-like External harvested vessel attachment

  7. Possible Solution 2 “Umbrella” grafting device Circular surface is inserted into coronary artery and adheres to inner vessel surface Provides a stable vessel connection to facilitate suturing

  8. Progress Made • Redirected project toward efficient suturing techniques with improved stabilization • Obtained feedback from biomaterials experts • Utilized Innovation Workbench • Built crude models

  9. Current Status • Using Ratner as biomaterial reference • Seeking feedback from Dr.’s Greelish and Merrill regarding models • Acquired access to Dr. Jansen’s lab and storage facility • Narrowing solution options

  10. Future Plans • Develop prototypes • Continue researching possible solutions • Continue consultation with surgeons and engineers for feedback • Test scaled down prototypes on dog and pig hearts • Alter design based on feedback and prototype test results

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