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MEDS 371 Auditory system II: hindbrain. Dr. Duck O. Kim. cat brain dissected showing auditory system. cerebellum. auditory cortex. inferior colliculus. cochlear nucleus. medial geniculate. auditory nerve. Oliver. dorsal. anterior. tonotopic organization of CN. cat CN. h.

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MEDS 371

Auditory system II:

hindbrain

Dr. Duck O. Kim


Cat brain dissected showing auditory system
cat brain dissected showing auditory system

cerebellum

auditory

cortex

inferior

colliculus

cochlear

nucleus

medial

geniculate

auditory nerve

Oliver


dorsal

anterior

tonotopic

organization

of CN

cat CN

h

DCN

h

AVCN

CN: cochlear nucleus

DCN: dorsal CN

AVCN: anterovent. CN

PVCN: posterovent. CN

PVCN

h

Arnesen & Osen, 1978


type I (95%)

1. spherical bushy cell; AVCN

2. stellate cell; VCN

3. globular bushy cell; AVCN

4. octopus cell; PVCN

5. fusiform cell; DCN

Kiang, 1975


cells in the cochlear nucleus

PST histogram

F

O

PST histogram

GB

spiral ganglion

neuron

type I (95%)

S

SB

Kiang, 1975


end bulbs of Held at bushy cells of the AVCN

Ryugo, 1999, Fig-10


intrinsic properties

EPSPs

cochlear nucleus

neurons

intracellular recording

in brain-slice

preparation

Oertel et al., 1988


The "where-processing" of sound:

Neural representation of auditory space

requires de novo computation

unlike the retinotopic map.



Sound localization cues rabbit

* interaural time difference (ITD)

5 μsec; ~ 1 deg azimuth.

* interaural level difference (ILD)

* spectral cues

*direct/reverberant energy ratio; distance

virtual auditory space


cortex rabbit

thalamus

midbrain

CN & SOC

pons

the ascending

auditory pathways

of the cat

binaural &

monaural

pathways

Brodal, 1981


Brodal Fig 9-8 rabbit

mso: medial sup. olive; lso: lateral sup. olive

ntb: nuc. trazepoid body; ic: inf. coll.


LSO rabbit

LSO

MSO

MSO

MNTB

MNTB

cat superior olivary complex

D

M

(axons & endings)

(somata & dendrites)

Tsuchitani, 1978, Fig. 10


ILD processing in LSO rabbit

Purves Fig 13-14A


ILD processing in LSO rabbit

Purves Fig 13-14B


model for ITD coding employing rabbit

neural delay lines & coincidence detectors

MSO neurons act as

coincidence detectors.

best ITD 1 = 0 ms; sound in front

best ITD 2 = 50 ms

best ITD 3 = 100 ms

...

best ITD 7 = 700 ms;

sound on opposite side

maximum firing when

left (acoustic delay + neural delay) =

right (acoustic delay + neural delay)

Jeffress, 1948; Kuwada



Inferior colliculus neurons show azimuth tuning. rabbit

10 dB

30 dB

50 dB

Kuwada, Bishop, Alex, Condit, Kim, 2011, J. Neurophys.


auditory & rabbit

somatosen.

inputs

Sup. coll. contains visual and auditory space maps.

Purves Box 20B


cortex rabbit

thalamus

midbrain

CN & SOC

pons

the descending

auditory pathways

of the cat

Brodal, 1981


olivocochlear neurons rabbit

LOC:

lateral

olivocochlear

MOC:

medial

olivocochlear

Warr et al., 2002


afferent rabbit

afferent

inner hair cell

outer hair cell

afferent

nerve

ending

afferent

nerve

ending

*

afferent

nerve

fibers

efferent

nerve

ending

*

efferent

nerve

fibers

Smith, 1975


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