Hardy-Weinberg Rule. Allele frequencies when populations are NOT evolving. Hardy-Weinberg Rule. Allele frequencies will NOT change (stay in equilibrium) if the following conditions are met: No mutation Large population isolated from other populations of same species Random mating
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Allele frequencies when populations are NOT evolving
p2 + 2pq + q2 = 1
P2 is AA
pq is Aa ( x 2 because aA also)
q2 is aa
You can use the formula to track alleles from one generation to the next to see if the gene frequencies are changing.
p= frequency of allele A
q= frequency of allele a
p+ q = 1Hardy-Weinberg Rule