IL-22
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IL-22. 20. 18. 100. 16. 90. 14. 80. 12. 70. 10. 60. 8. 50. 6. 40. 4. 30. 2. 20. 0. 10. 0. a. IL-22. IL-17A. IL-17F. mRNA level to HPRT (x10 -3 ). 200. 20000. 70000. 150. 15000. 50000. 100. 10000. 30000. 50. 5000. 10000. 0. 0. 0. 0. 1. 1. 100. 100.

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Suppl Figure 2

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Suppl figure 2

IL-22

20

18

100

16

90

14

80

12

70

10

60

8

50

6

40

4

30

2

20

0

10

0

a

IL-22

IL-17A

IL-17F

mRNA level to HPRT (x10-3)

200

20000

70000

150

15000

50000

100

10000

30000

50

5000

10000

0

0

0

0

1

1

100

100

500

500

0

0.5

0.5

10

10

100

1

500

0.5

10

FICZ (nM)

b

c

IL-17A

IL-22

IL-17A

IL-17F

2

50

70

40

% positive cells

1.5

60

30

1

% of positive cells

50

20

0.5

40

10

30

0

0

ctrl

ctrl

1.0 mM bNF

0.5 mM bNF

1.0 mM bNF

0.5 mM bNF

0.1 mM bNF

0.1 mM bNF

20

10

0

+FICZ

+FICZ

+FICZ

Suppl Figure 2


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