Protein structure
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Protein Structure. Biology/Chemistry of Protein Structure. Primary Secondary Tertiary Quaternary. Assembly Folding Packing Interaction. S T R U C T U R E. P R O C E S S. Primary Structure - Sequence. FOLDING. Basic Secondary structure. α -helix. β -sheet.

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Presentation Transcript

Biology chemistry of protein structure
Biology/Chemistry of Protein Structure

Primary

Secondary

Tertiary

Quaternary

Assembly

Folding

Packing

Interaction

S T R U C T U R E

P R O C E S S




Basic secondary structure
Basic Secondary structure

α-helix

β-sheet

Secondary structures, α-helix and β-sheet, have regular hydrogen-bonding patterns.


1 2 3 4
1’ > 2’ > 3’ > 4’ > …

Tertiary structure

Quaternary structure


X ray
X - Ray

X-ray Diffraction Pattern for a Protein




The database of experimentally derived structures of proteins nucleic acids and complexes
THE database of experimentally-derived structures of proteins, nucleic acids, and complexes

  • Access to structural information

  • Visualization

  • Analysis


Pdb growth and content
PDB Growth and Content

Macromolecules:

Proteins

Nucleic acids

Carbohydrates

Protein-nucleic acid complexes

Protein-carbohydrate complexes

Experimental Methods:

X-Ray Crystallography

NMR

more…








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