Protein structure
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Protein Structure PowerPoint PPT Presentation


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Protein Structure. Biology/Chemistry of Protein Structure. Primary Secondary Tertiary Quaternary. Assembly Folding Packing Interaction. S T R U C T U R E. P R O C E S S. Primary Structure - Sequence. FOLDING. Basic Secondary structure. α -helix. β -sheet.

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Protein Structure

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Protein structure

Protein Structure


Biology chemistry of protein structure

Biology/Chemistry of Protein Structure

Primary

Secondary

Tertiary

Quaternary

Assembly

Folding

Packing

Interaction

S T R U C T U R E

P R O C E S S


Primary structure sequence

Primary Structure - Sequence


Folding

FOLDING


Basic secondary structure

Basic Secondary structure

α-helix

β-sheet

Secondary structures, α-helix and β-sheet, have regular hydrogen-bonding patterns.


1 2 3 4

1’ > 2’ > 3’ > 4’ > …

Tertiary structure

Quaternary structure


X ray

X - Ray

X-ray Diffraction Pattern for a Protein


X ray1

X-Ray


Nmr there is no right answer

NMR – there is no right answer


The database of experimentally derived structures of proteins nucleic acids and complexes

THE database of experimentally-derived structures of proteins, nucleic acids, and complexes

  • Access to structural information

  • Visualization

  • Analysis


Pdb growth and content

PDB Growth and Content

Macromolecules:

Proteins

Nucleic acids

Carbohydrates

Protein-nucleic acid complexes

Protein-carbohydrate complexes

Experimental Methods:

X-Ray Crystallography

NMR

more…


Protein structure

PDB Homepage


An example 2ara

An Example – 2ARA


Protein structure

Search Methods


Protein structure

Advanced Search


Protein structure

Sequence Search


Example results

Example Results


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