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11.2 Blood: A Fluid Tissue. Pages 482-486. Function of Blood. Delivers oxygen to cells, picks up carbon dioxide Delivers nutrients to cells and collects wastes Temperature regulation Circulation of hormones. Components. Red blood cells White blood cells Platelets Plasma. Plasma.

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Function of blood
Function of Blood

  • Delivers oxygen to cells, picks up carbon dioxide

  • Delivers nutrients to cells and collects wastes

  • Temperature regulation

  • Circulation of hormones


Components
Components

  • Red blood cells

  • White blood cells

  • Platelets

  • Plasma


Plasma
Plasma

  • 90% water

  • Dissolved O2, CO2, glucose, vitamins and minerals, wastes

  • Proteins:for clotting, immunity and water balance

  • Dissolve ions Na+, K+, Ca2+, Cl-, and HCO3-


Albumins
Albumins

  • Control water levels in the blood


Globulins
Globulins

  • Transport lipids, cholesterol, fat-soluble vitamins (A,D,E and K), some minerals

  • Immunoglobulins (antibodies)


Fibrinogen
Fibrinogen

  • Role in blood clotting


Serum
Serum

  • Plasma with fibrinogen and clotting factors removed.


Erythrocytes
Erythrocytes

  • Red blood cells

  • Biconcave disks

  • 135 RBC’s per mm

  • Formed from stem cells in bone marrow

  • No nucleus in mature cells

  • Lifespan 120 days

  • Liver and spleen break RBC’s down


Leukocytes
Leukocytes

  • White blood cells

  • nucleus

  • Granular leukocytes (neutrophils, eosinophils and basophils) kill bacteria

  • Agranular leukocytes (lymphocytes, monocytes) engulf bacteria

  • Pus



Platelets
Platelets

  • Protection

  • Produced in the bone marrow

  • Blood clotting

  • Platelets and fibrinogen form clot


Blood count
Blood Count

  • Hemocytometer

  • Anemia (low RBC coun t)


Plasma1
Plasma

Plasma 55-58%

  • Water 91-92%

  • Plasma proteins 7-8%

  • Dissolved things 1-2%


Cells
Cells

  • Platelets 250000-300000 per microlitre

    Leukocytes

  • Neutrophils 3000-6750

  • Lymphocytes 1000-2700

  • Monocytes/macrophages 150-720

  • Eosinophils 100-360

  • Basophils 25-90

  • Erythrocytes 4 800 000-5 400 000


Blood types
Blood Types

  • Markers A and B

  • Type A…marker A

  • Type B…marker B

  • Type AB…marker A & B

  • Type O…no marker


Immune response
Immune response

  • Transfusions of blood with a different marker causes an immune response


Rhesus factor
Rhesus Factor

  • 85% are Rh-positive


Artificial blood
Artificial Blood

  • HBOC hemoglobin-based oxygen carriers

  • PFCE perfluorocarbon emulsions


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