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Primer on the Olfactory Bulb and Antennal Lobe

Primer on the Olfactory Bulb and Antennal Lobe. Brief comparative introduction of: Neurons Synaptic interactions. Olfaction: common evolutionary problems…. …common solutions. The AL and OB: Macroscopic Relations. Brain nerve I. OB projects to various brain centers. J. H. Martin, 1989.

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Primer on the Olfactory Bulb and Antennal Lobe

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  1. Primer on the Olfactory Bulb and Antennal Lobe • Brief comparative introduction of: • Neurons • Synaptic interactions

  2. Olfaction: common evolutionary problems… …common solutions

  3. The AL and OB: Macroscopic Relations Brain nerve I OB projects to various brain centers J. H. Martin, 1989

  4. The Mammalian Sensory Epithelium Each olfactory receptor neuron (ORN) expresses only one gene coding an odorant receptor protein. L. Buck and R. Axel (1991) Cell 65, 175-187 Fascicles G. M. Shepherd, 2004

  5. The Insect Sensory Epithelium

  6. OB Intrinsic (local) and Principle (output) Neurons

  7. Synaptic interactions within the OB glomeruli

  8. Synaptic interactions within the AL glomeruli AL’s BMI-sensitive Receptors: D.2.2.1 D.2.3.1 D.2.3.3 + + – cholinergic ORN input PN (output) GABAergic LN’s + AL glomerulus

  9. AL Intrinsic (local) and Principle (output) Neurons AL MB http://www.biozentrum.uni-wuerzburg.de/fileadmin/REPORT/GENET/genet010.htm - + - + + + LH

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