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Division of Yonsei Dental Sciences

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Division of Yonsei Dental Sciences. ○ Vision And Objectives. “Yonsei Standing Proud”. Through the Global 5-5-10 Project for Division of Dental Sciences, Yonsei University School of Dentistry will become one of the world’s leading educational and research institutes.

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Presentation Transcript
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Division of Yonsei

Dental Sciences

slide2

○ Vision And Objectives

“Yonsei Standing Proud”

Through the Global 5-5-10Project for Division ofDental Sciences, Yonsei University School of Dentistry will become one of the world’s leading educational and research institutes.

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○ Research Fields

  • ● Cell signaling
  • - Cell signaling associated with bone formation
  • Development of drugs that induce bone formation and
  • prevent bone absorption

Cell Signaling in Bone cells

▶ Cell signaling associated with bone remodeling

▶ Development of drugs to induce bone formation and prevent bone resorption

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○ Research Fields

  • ● Tissue regeneration
  • Artificial tooth and bone formation
  • using organ culture system
  • Orofacial hard tissue regeneration
  • with an aid of artificial teeth and
  • bones

▶ Construction of artificial tooth and periodontium

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○ Research Fields

● Development of dental materials and medical devices

▶ Development and application of bioceramics for bone replacement

▶ Development of new dental casting metals

● Digital imaging

▶ Development of diagnosis technique using digital image

▶ Data analysis using 3-D image

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○ Research Fields

● Periodontal disease and immune system

▶ Treatment and prevention of periodontal disease

▶ Drug development inducing periodontal tissue regeneration

● Carcinogenesis and cancer prevention

▶ Research on the carcinogenesis

▶ Mechanism of Carcinogenesis

▶ Drug development for cancer treatment and prevention

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○ Activities and Outputs

● Activities

Student exchange

program

▶ Tokyo Dental college

▶ UCLA

▶ University of

Pennsylvania

▶ Tuft University

● Outputs

▶ Molecular interactions between Tbx3 and Bmp4 and a model for dorsoventral positioning of mammary gland development. Proc Natl Acad Sci USA, 103(45):16788-16793, 2006

▶A Wnt-Axin2-GSK3 cascade regulates Snail activity in breast cancer cells. Nature Cell Biology. 8(12):1398-1406, 2006

▶Xanthorrhizol inhibits 12-0-tetradecanoylphobol-13-acetate-induced acute inflammation and two-stage mouse skin carcinigenesis by blocking the expression of ornithine decarboxylase, caclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nucleas factor-kappa B. Carcinogenesis. 28(6):1224-1231, 2007

▶Skeletal muscle dressed in SOCs. Nature Cell Biology. 10(6):639-641, 2008

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○ Contact Point

● Director: Syng-Ill Lee, D.D.S., Ph.D.

● Address: Department of Oral Biology, Yonsei University College of Dentistry 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea

● Tel: +82-2-2228-3052

Fax: +82-2-364-1085

● E - mail: [email protected]

Website:http://bk21-dentsci.yonsei.ac.kr

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