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Literature Sources in Pharmacovigilance. Sten Olsson WHO-Uppsala Monitoring Centre Sweden. Original journals. Positive Fast Comprehensive information Negative Expensive Low coverage JAMA Therapie New Engl J of Med Brit Med Journal The Lancet. http://bmj.com/.

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Literature Sources in Pharmacovigilance

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Literature sources in pharmacovigilance l.jpg

Literature Sources in Pharmacovigilance

Sten Olsson

WHO-Uppsala Monitoring Centre Sweden


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Original journals

  • Positive

  • Fast

  • Comprehensive information

  • Negative

  • Expensive

  • Low coverage

  • JAMA

  • Therapie

  • New Engl J of Med

  • Brit Med Journal

  • The Lancet


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http://bmj.com/


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Journals of special interest

  • Pharmacoepidemiology & Drug Safety

  • Drug Safety

  • Risk & Safety in Medicine


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Bibliographic titles review

  • Positive

    Fast

    High coverage

  • Negative

    Minimal detail

    Current Contents


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Secondary review journals

  • Positive

    - Quite fast

    - Some detail

    - High coverage

  • Negative

    - Lack of detail

    - Difficult to search systematically - (Cost)

  • Reactions Weekly


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Positive

- Assessment of significance

- Easy access

Negative

- Lack of detail

- Not completely up-to-date

Meyler's Side Effects of Drugs

Side Effects of Drugs Annual

Adverse Drug Reaction Bulletin

Prescrire

Expert Opinion on Drug Safety

Expert annotated review


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Reference books

  • Martindale – the extra Pharmacopoea

  • Meyler’s Side Effects of Drugs

  • Pharmacovigilance from A-Z

  • Dictionary of Pharmacovigilance


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Textbooks

  • Drug induced diseases

    • Textbook of Adverse Drug Reactions (Davies, 1998)

    • Avery's Drug Treatment (Speight, 1997)

    • Drug Benefits and Risks (van Boxtel, Santoso, Edwards, 2002)

    • Adverse Drug Reactions (Lee, 2001)


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Methodology

  • Pharmacovigilance (Mann, Andrews, 2002)

  • Pharmacoepidemiology (Strom, 2000)

  • Stephens’ Detection of New Adverse Drug Reactions (Talbot, Waller, 2004)

  • Adverse Drug Reactions: A practical guide to Diagnosis and Management (Bénichou, 1996)


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Adverse Drug Interactions(Griffin, D'Arcy, 1997)

Drugs in Pregnancy and Lactation (Briggs, Freeman,Yaffe, 1998)

Drug-induced Ocular Side Effects (Fraunfelder, 2002)

Adverse Effects of Herbal Drugs(De Smet et al 1992)

Adverse Events Associated with childhood vaccines (Instit of Med, 1994)

Responsibility for Drug-induced Injury (Dukes, Mildred, Swartz, 1998)

Safety of Anaesthetic Drugs (Naguib, 1998)

To Heal And Harm: An economic view on drug safety (Silcock and Pritchard, 2003)

Reference booksAddressing specific problem areas


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References online

  • Micromedex

    • Includes Martindale, PDR, Alternative Medicines and Index Nominum

  • Merck Manual

    • Includes: The Merck Manual of Diagnosis and Therapy

  • SAM=Scientific American Medicine


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Computerized literature screening (1/2)

  • Positive

    • High coverage

    • High specificity of search

  • Negative

    • Requires equipment & skill

    • Lack of detail


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Computerized literature screening (2/2)

  • Medline

    • Pubmed is using the MeSH (Medical Subject Headings) terminology.

  • EMBASE

  • Current Contents on CD

  • Reactions Weekly on-line


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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed


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WHO Publications

  • WHO Pharmaceuticals Newsletter

  • WHO Drug Information

  • Dialogue in Pharmacovigilance

  • Viewpoint 1 & 2

  • Expecting the Worst

  • Uppsala Reports


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NATIONAL ADR BULLETINS

  • Presciber Update, New Zealand

  • Australian Adverse Reactions Bulletin

  • Signals in Adverse Drug Reactions Monitoring, The Philippines

  • Butlletí Groc and many other regional bulletins, Spain

  • Information från Läkemedelsverket, Sweden

  • Drug Information Bulletin, Tanzania


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NATIONAL ADR BULLETINS (2)

  • Berita Ubat-Ubatan, Malaysia

  • Folia Pharmacoterapeutica, Belgium

  • Canadian Adverse Drug Reaction Newsletter

  • TABU, Finland

  • Drug Safety Newsletter, Ireland

  • Information on Adverse Reactions to Drugs, Japan

  • Adverse Drug Reaction News, Singapore


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