Retinitis pigmentosa
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Retinitis Pigmentosa. Jackson, Jefferson, Klecka , Castillo. Retinitis Pigementosa (RP). RP refers to a group of inherited disease causing retinal degeneration. Retinal degeneration. Symptoms. Decreased vision or in low light Loss of side (peripheral) vision, causing “tunnel vision”

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Retinitis Pigmentosa

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Retinitis pigmentosa

Retinitis Pigmentosa

Jackson, Jefferson, Klecka, Castillo


Retinitis pigementosa rp

Retinitis Pigementosa (RP)

  • RP refers to a group of inherited disease causing retinal degeneration.

  • Retinal degeneration


Symptoms

Symptoms

  • Decreased vision or in low light

  • Loss of side (peripheral) vision, causing “tunnel vision”

  • Loss of central vision (in advanced cases)


Decreased vision at night

Decreased vision at night


Peripheral vision

Peripheral vision


Loss of central vision

Loss of central vision


Causes

Causes

  • RP can run in families

  • Disorder can be caused by genetic defects

  • Cells controlling night vision are called “rods”

  • Retinal cone cells are damaged the most


Exams and test

Exams and test

  • Color vision

  • Retina by ophthalmoscopy after pupils been dilated

  • Fluorescein angiography

  • Intraocular pressure

  • Measurement of electrical activity (electroretinogram)

  • Pupil reflex test

  • Retinal photography

  • Refraction test

  • Retinal Photography

  • Side vision test (visual field test)

  • Slit lam examination

  • Visual acuity


Treatments

Treatments

  • Gene Therapy

  • Stem cell research

  • Eye implants

  • Pharmacology and medicines

  • Docosahexaenoic acid (DHA)

  • Vitamin A antioxidants


Genetic mutations that could cause rp

Genetic mutations that could cause RP

  • Autosomal recessive

  • Autosomal dominant

  • X linked


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