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NEW OPTIONS IN PROSTATE CANCER TREATMENT Presented by Triangle Urology Associates, P.A. PROSTATE CANCER: The #1 cancer in males. Second leading cause of cancer related deaths among men 1 out of 6 men has a chance of developing prostate cancer in his lifetime

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NEW OPTIONS IN PROSTATE CANCER TREATMENT Presented by Triangle Urology Associates, P.A.

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NEW OPTIONS IN PROSTATE CANCER TREATMENTPresented byTriangle Urology Associates, P.A.


PROSTATE CANCER:The #1 cancer in males

  • Second leading cause of cancer related deaths among men

  • 1 out of 6 men has a chance of developing prostate cancerin his lifetime

  • Majority of cases occur after age 65


EARLY DETECTION IS KEY

  • Disease has “silent” progression in early stages

  • 21% of cases are discovered after disease is advanced

  • If detected early, cure rate is nearly 100%


PROSTATE ANATOMY

  • Walnut-sized gland below the bladder

  • Surrounds the urethra


PROSTATE CANCER WARNING SIGNS

  • Weak or interrupted urine stream

  • Difficulty urinating/frequent urination

  • Painful/burning urination

  • Blood in urine

  • Pain in back, hips, pelvis

  • Often no symptoms at all!


DIAGNOSING PROSTATE CANCER

  • Digital Rectal Exam (“DRE”)

  • Prostate Specific Antigen (“PSA”) blood test

  • Screening (DRE, PSA) is recommended:

    • Annually for men 50+ years

    • At age 40 for higher risk patients (African-American,

    • Family history of prostate cancer)

  • Elevated PSA levels suggest possible presence of cancer, gland enlargement or infection


IF PSA OR DRE IS ABNORMAL

  • Additional tests may be done to confirm presence of cancer:

    • Imaging of the prostate (ultrasound, MRI, CT)

    • Needle biopsy - small tissue sample obtained with a needle and analyzed in lab


AFTER THE DIAGNOSIS

  • Grading the tumor

  • Staging the cancer

  • Considering a treatment plan


GRADING THE TUMOR

  • Determines how fast the tumor is growing

  • Rated on a “Gleason Scale” of 2-10

  • Most localized prostate cancers are low-to-intermediate grade


CANCER STAGING

  • Measures how far cancer has spreadoutside the gland

  • Two common staging systems:

    • TNM Staging System

    • Stage I-IV (A-D)


THE GOOD NEWS

If detected early, prostate cancer is highly treatable!


TREATMENT OPTIONS

  • Watchful waiting

  • Surgery

  • External beam radiation therapy

  • Hormone therapy

  • Brachytherapy (seed implantation)

  • Combination Therapy


WATCHFUL WAITING

  • May be used for slow-growing tumors or elderly patients

  • Requires frequent check-ups on progress of tumor

  • Does not include any active treatment


SURGERY (RADICAL PROSTATECTOMY)

  • Involves removal of entire prostate gland and surrounding tissue

  • Can be very effective if cancer is confined to gland

  • Requires hospitalization

  • Side effects include possible impotence and incontinence


EXTERNAL BEAM RADIATION

  • Uses radiation (x-ray) to destroy cancer cells

  • A common treatment technique in early cancers

  • Requires daily treatment for 8-9 weeks

  • Side effects may include:

    • Incontinence– Urinary or rectal problems

    • Skin irritation

    • Impotence

    • Fatigue and bowel irritation


HORMONE THERAPY

  • Lowers level of male hormones (androgens) to shrink gland and slow tumor growth

  • Sometimes used in combination withother therapies

  • A treatment but not a “cure”


Now, an effective treatment option that also helps preserve patient quality of life: Brachytherapy


WHAT IS BRACHYTHERAPY?

  • Implantation of radioactive “seeds” directly into the prostate gland

  • Seeds deliver high-dose radiation directly to the site of the cancer

  • Seeds release radiation over 3-9 months


BRACHYTHERAPY: PROVEN EFFECTIVE

  • Modern technique developed in the 1980’s

  • Involves a team of specialists - urologist, radiation oncologist, medical physicist

  • Over 100,000 patients treated successfully

  • Published studies show results comparable to surgery and external radiation1,2

1. Ragde H, Korbe LJ, Elgamal AA, et al. Modern Prostate Brachytherapy: Prostate Specific Antigen results in 219 patients with

up to 12 years of observed follow-up. Cancer. 2000;89(1):135-141.

2. Sharkey J, Chovnick SD, Behar RJ, et al. Outpatient ultrasound-guided Palladium-103 brachytherapy for localized

adenocarcinoma of the prostate: A preliminary report of 434 patients. Urology. 1998;51(5):796-803.


How are We Different?

  • Piedmont Prostate Center in conjunction with your urologist is the only medical clinic in North Carolina that can offer in office prostate brachytherapy.

  • No hospitalization required!

  • The entire procedure is performed in the comfort of the urologist’s office.


THE BRACHYTHERAPY PROCEDURE

  • The entire procedure is usually done in 1-2 hours on an outpatient basis under local pain control.

  • State of the art equipment and personnel specifically designed or trained for Brachytherapy is brought to you.

  • No general or spinal anesthesia required!

  • Usually no catheter required post procedure.


SMALL SEEDSBIG ADVANTAGES

  • No major surgery required

  • No daily treatments

  • Normal activity is resumed quickly

  • Reduced risk of impotence, incontinence

  • Completely outpatient. No hospitalizations or need for expensive anesthesia.


CHOOSING THE RIGHT OPTION FOR YOU

  • Learn the facts

  • Talk to us or

    your doctor

  • Get annual check-ups: DRE and PSA

  • Live free of cancer


Triangle Urology AssociatesCathy Stutts, RN919-313-3609cathys@triangleurologync.com


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