Which nvaf patients are candidates for tsoacs
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Which NVAF patients are candidates for TSOACs ? PowerPoint PPT Presentation


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Which NVAF patients are candidates for TSOACs ?. Compelling candidates Have NVAF and meet CHADS 2 or CHA 2 DS 2 VASc criteria for anticoagulation AND ≥1 of the following Poor INR control in spite of good compliance with warfarin Unusual difficulty with regular INR checks

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Which NVAF patients are candidates for TSOACs ?

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Which nvaf patients are candidates for tsoacs

Which NVAF patients are candidates for TSOACs?

  • Compelling candidates

    • Have NVAF and meet CHADS2 or CHA2DS2VASc criteria for anticoagulation AND ≥1 of the following

      • Poor INR control in spite of good compliance with warfarin

      • Unusual difficulty with regular INR checks

      • True warfarin allergy

      • Understand potential disadvantages (e.g. lack of antidote) and are willing to trade them for convenience of no lab monitoring

  • Less compelling candidates

    • Have indications other than NVAF for anticoagulation (e.g. mechanical heart valve) or an unacceptable risk-benefit ratio for warfarin use

    • Are stable on warfarin with TTR > 72%

    • Have CrCl < 30 ml/min

    • Have poor INR control due to poor compliance

    • Potential financial barriers to care (e.g. no prescription benefit coverage)

    • Other questionable characteristics

      • Age ≥ 75 yoa

      • History of cardiac disease

      • History of GI bleed


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