which nvaf patients are candidates for tsoacs
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Which NVAF patients are candidates for TSOACs ?. Compelling candidates Have NVAF and meet CHADS 2 or CHA 2 DS 2 VASc criteria for anticoagulation AND ≥1 of the following Poor INR control in spite of good compliance with warfarin Unusual difficulty with regular INR checks

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which nvaf patients are candidates for tsoacs
Which NVAF patients are candidates for TSOACs?
  • Compelling candidates
    • Have NVAF and meet CHADS2 or CHA2DS2VASc criteria for anticoagulation AND ≥1 of the following
      • Poor INR control in spite of good compliance with warfarin
      • Unusual difficulty with regular INR checks
      • True warfarin allergy
      • Understand potential disadvantages (e.g. lack of antidote) and are willing to trade them for convenience of no lab monitoring
  • Less compelling candidates
    • Have indications other than NVAF for anticoagulation (e.g. mechanical heart valve) or an unacceptable risk-benefit ratio for warfarin use
    • Are stable on warfarin with TTR > 72%
    • Have CrCl < 30 ml/min
    • Have poor INR control due to poor compliance
    • Potential financial barriers to care (e.g. no prescription benefit coverage)
    • Other questionable characteristics
      • Age ≥ 75 yoa
      • History of cardiac disease
      • History of GI bleed
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