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Outcome after Surgical Resections of (recurrent) Chest Wall Sarcomas. Is it worthwhile?. Michael Wouters Bert van Geel Lotte Nieuwenhuis Harm van Tinteren Cees Verhoef Houke Klomp Frits van Coevorden. Resections for Chest Wall Sarcoma Background. Sarcomas
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Outcome after Surgical Resectionsof(recurrent) Chest Wall Sarcomas Is it worthwhile? Michael Wouters Bert van Geel Lotte Nieuwenhuis Harm van Tinteren Cees Verhoef Houke Klomp Frits van Coevorden
Resections for Chest Wall SarcomaBackground Sarcomas • 1 % of all malignancies in adults • 10-15% arise in the chest wall • best controlled bywide (full-thickness) chest wall resections • neo-(adjuvant) radio- or chemotherapy
Resections for Chest Wall sarcomaObjective To evaluate: - morbidity, mortality and (disease-free) survival - outcome for primary and recurrent sarcomas of the chest wall
Resections for Chest Wall sarcomaMethods • retrospective study • 2 tertiary referral centers in the Netherlands • 1980 – 2006 • any sarcoma involving: • Ribs • Sternum • Costo-vertebral junction • Vertebral body • full-thickness Chest Wall resection
Resections for Chest Wall sarcomaFull-thickness Chest Wall resection
Resection of Chest Wall sarcomaPatients median follow-up time: 74 months
Resections of Chest Wall sarcomaResults / Patient & Tumor characteristics
Resections of Chest Wall sarcomaResults / Patient & Tumor characteristics
Resections of Chest Wall sarcomaResults / Treatment characteristics
Resections of Chest Wall sarcomaResults / Outcome / Morbidity
Resection of Chest Wall sarcomaResults / Outcome / DFS vs OS DFS OS
Resection of Chest Wall sarcomaResults / Outcome / Recurrences
Resection of Chest Wall sarcomaResults / Outcome / Recurrences
Resection of Chest Wall sarcomaResults / Outcome / Recurrences
Resections for Chest Wall SarcomaDiscussion • Primary and Recurrent Chest Wall sarcomas have different recurrence patterns. • This selection of locally recurrent Chest Wall sarcomas has less tendency to metastasize.
Resections for Chest Wall SarcomaConclusions • Safe and effective procedure, even in locally recurrent sarcomas • 5-year survival after resection of recurrent chest wall sarcomas is ‘worthwhile’! • Recurrent chest wall sarcomas should be resected if technically possible.