Chapter 44 Disorders of the Skeletal System: Metabolic and Rheumatic Disorders. Normal Bone Remodeling. Osteoblasts are “bone building” cells They control bone remodeling by: Laying down new bone Secreting a compound (RANK ligand) that controls the osteoclasts , the “bone breaking” cells
Tell whether the following statement is true or false.
When osteoblasts work harder than osteoclasts, bones grow.
Osteoblasts build bone tissue; when they are more active than osteoclasts, bone grows. When osteoclasts work harder than osteoblasts, more bone is broken down.
How is bone remodeling affected by the following?
Why are each of these people prone to osteoporosis?
Which bone disorder is characterized by “soft” bones?
Calcium need vitamin D in order to be absorbed. In the case of vitamin D deficiency (rickets), calcium cannot be absorbed, and bones become soft.
SLE produces antibodies against all but which of the following?
SLE is an autoimmune disease that results in the production of the following antibodies: antinuclear antibodies, and antibodies against RBCs, platelets, and coagulation factors. WBCs are not affected.